| Jurisdiction: | Diocese |
| San Isidro | |
| Latin: | Dioecesis Sancti Isidori in Argentina |
| Local: | Diócesis de San Isidro |
| Country: | Argentina |
| Metropolitan: | Buenos Aires |
| Province: | Buenos Aires |
| Area Km2: | 1,379 |
| Population: | 1,145,000 |
| Population As Of: | 2010 |
| Catholics: | 1,091,000 |
| Catholics Percent: | 95.3 |
| Parishes: | 66 |
| Denomination: | Roman Catholic |
| Rite: | Roman Rite |
| Established: | 11 February 1957 |
| Cathedral: | Cathedral of St Isidore the Laborer in San Isidoro |
| Patron: | St Isidore the Laborer |
| Bishop Title: | Bishop |
| Bishop: | Óscar Vicente Ojea |
| Metro Archbishop: | Mario Aurelio Poli |
| Emeritus Bishops: | Jorge Casaretto |
| Website: | Website of the Diocese |
The Diocese of San Isidro is an administrative division of the Roman Catholic Church in Argentina. It was established on 11 February 1957 and covers an area of .