| Jurisdiction: | Diocese |
| Qacha’s Nek | |
| Latin: | Dioecesis Qachasnekensis |
| Country: | Lesotho |
| Metropolitan: | Maseru |
| Rite: | Roman Rite |
| Area Km2: | 11,409 |
| Population: | 382,933 |
| Population As Of: | 2004 |
| Catholics: | 189,551 |
| Catholics Percent: | 49.5 |
| Bishop: | Joseph Mopeli Sephamola, O.M.I. |
| Sui Iuris Church: | Latin Church |
| Cathedral: | Cathedral of the Holy Redeemer |
The Roman Catholic Diocese of Qacha's Nek (la|Qachasneken(sis)) is a diocese located in the town of Qacha’s Nek in the ecclesiastical province of Maseru in Lesotho.