| Jurisdiction: | Diocese |
| Opole | |
| Latin: | Dioecesis Opoliensis |
| Local: | Diecezja Opolska |
| Country: | Poland |
| Metropolitan: | Katowice |
| Rite: | Latin Rite |
| Cathedral: | Katedra św. Krzyża (Cathedral of the Holy Cross) |
| Area Km2: | 8,033 |
| Population: | 850,693 |
| Population As Of: | 2021 |
| Catholics: | 783,056 |
| Catholics Percent: | 92.0 |
| Auxiliary Bishops: | Rudolf Pierskała Waldemar Musioł |
| Emeritus Bishops: | Alfons Nossol Paweł Stobrawa |
| Map: | Roman Catholic Diocese of Opole location map.svg |
| Website: | Website of the Diocese |
| Denomination: | Catholic Church |
The Diocese of Opole (Latin: Dioecesis Opoliensis) is a Latin diocese of the Catholic Church located in the city of Opole in the ecclesiastical province of Katowice in Poland.