| Jurisdiction: | Diocese |
| Mocoa–Sibundoy | |
| Latin: | Dioecesis Mocoënsis-Sibundoyensis |
| Rite: | Latin Rite |
| Established: | 8 February 1951 (years ago) |
| Cathedral: | Catedral de San Alfonso Maria de Liguori in Sibundoy |
| Cocathedral: | Co-Catedral de San Miguel Arcángel in Mocoa |
| Area Km2: | 25,000 |
| Population: | 290,200 |
| Population As Of: | 2004 |
| Catholics: | 255,000 |
| Catholics Percent: | 87.9 |
| Metro Archbishop: | Omar de Jesús Mejía Giraldo |
| Bishop: | Luis Albeiro Maldonado Monsalve |
| Emeritus Bishops: | Fabio de Jesús Morales Grisales, C.Ss.R. |
| Map: | Mapa Diocesis de Mocoa - Sibundoy.svg |
| Website: | www.diocmocoasibundoy.org |
The Roman Catholic Diocese of Mocoa–Sibundoy (Latin: Mocoën(sis)-Sibundoyen(sis)) is a diocese located in the cities of Mocoa and Sibundoy in the ecclesiastical province of Florencia in Colombia.