| Jurisdiction: | Diocese |
| Mackenzie–Fort Smith | |
| Latin: | Dioecesis Mackenziensis–Arcis Smith |
| Coat: | File:Diocese_of_Mackenzie–Fort_Smith.jpg |
| Coat Size: | 200px |
| Coat Caption: | Coat of Arms |
| Country: |  Canada |
| Province: | Grouard-McLennan |
| Headquarters: | Yellowknife |
| Area Km2: | 1,523,400 |
| Catholics: | 28,540 |
| Catholics Percent: | 67.9 |
| Denomination: | Catholic |
| Sui Iuris Church: | Latin Church |
| Rite: | Roman Rite |
| Cathedral: | St. Joseph Cathedral |
| Bishop: | Jon Hansen, C,Ss.R. |
| Metro Archbishop: | Gérard Pettipas, C.Ss.R. |
| Emeritus Bishops: | Denis Croteau |
| Map: | Bistum Makenzie-Fort Smith.svg |
The Diocese of Mackenzie–Fort Smith (Latin: Dioecesis Mackenziensis–Arcis Smith) is a Latin Church ecclesiastical territory or diocese of the Catholic Church that includes the Northwest Territories, the northern extremity of Saskatchewan and the extreme west of the Territory of Nunavut in Canada. Bishop Jon Hansen,C.Ss.R. currently serves as Bishop of Mackenzie – Fort Smith, Canada.
Originally created in 1901 as the Vicariate Apostolic of Mackenzie, it was elevated to a full episcopal see in 1967.
As of 2004, the diocese contained 46 parishes and missions, 4 active diocesan priests, 7 religious priests, and 28,540 Catholics. At the time, it also had 16 women religious, 8 religious brothers, and 3 permanent deacons. One famous parish is Our Lady Of Victory Church in Inuvik.
The following is a list of the bishops of Mackenzie-Fort Smith and their terms of service: