| Jurisdiction: | Diocese |
| Lira | |
| Latin: | Dioecesis Lirensis |
| Country: |  Uganda |
| Metropolitan: | Gulu |
| Rite: | Latin Rite |
| Area Km2: | 12,030 |
| Population: | 1,751,700 |
| Population As Of: | 2004 |
| Catholics: | 980,600 |
| Catholics Percent: | 56.0 |
| Bishop: | Sanctus Lino Wanok |
| Emeritus Bishops: | Giuseppe Franzelli, M.C.C.I. |
The Roman Catholic Diocese of Lira (Latin: Liren(sis)) is a diocese located in the city of Lira in the ecclesiastical province of Gulu in Uganda.