| Jurisdiction: | Diocese |
| Keta–Akatsi | |
| Latin: | Ketaensis-Akatsiensis |
| Country: |  Ghana |
| Metropolitan: | Accra |
| Rite: | Latin Rite |
| Area Km2: | 7,470 |
| Population: | 753,424 |
| Population As Of: | 2004 |
| Catholics: | 117,998 |
| Catholics Percent: | 15.7 |
| Bishop: | Gabriel Edoe Kumordji, S.V.D |
| Emeritus Bishops: | Anthony Kwami Adanuty |
The Roman Catholic Diocese of Keta–Akatsi (Latin: Ketaën(sis)–Akatsien(sis)) is a suffragan Latin diocese in the ecclesiastical province of Accra in Ghana, yet still depends on the missionary Roman Congregation for the Evangelization of Peoples.
The bishops' seat is Christ the King Cathedral, in Akatsi. The diocese also contains a co-cathedral: St. Michael's Cathedral, in the city of Keta.
It was established on March 15, 1923 as Apostolic Vicariate of Lower Volta (Volta Inférieur/Inferiore), on territories split off from the Apostolic Vicariate of Gold Coast (Ghana) and Apostolic Vicariate of Togo (in Togo) .It was then promoted on April 18, 1950 as Diocese of Keta.It lost territory on 1956.04.23 to establish Diocese of Navrongo.On June 20, 1975 it was renamed as Diocese of Keta–Ho.It was again renamed on December 19, 1994 as Diocese of Keta–Akatsi, having lost territories to establish Diocese of Ho and Diocese of Jasikan.
As per 2014, it pastorally served 134,600 Catholics (15.4% of 875,000 total) on 7,470 km² in 12 parishes and 6 missions with 55 priests (49 diocesan, 6 religious), 27 lay religious (6 brothers, 21 sisters) and 34 seminarians.
(all Roman rite; until 1976, European missionary members of Latin congregations, when the then auxiliary bishop was appointed as ordinary)