| Jurisdiction: | Diocese |
| Border: | catholic |
| Inhambane | |
| Latin: | Dioecesis Inhambanianus |
| Country: | Mozambique |
| Headquarters: | Inhambane |
| Metropolitan: | Maputo |
| Rite: | Latin Rite |
| Coordinates: | -23.8631°N 35.3793°W |
| Area Km2: | 68,476 |
| Population: | 1,762,604 |
| Population As Of: | 2017 |
| Catholics: | 324,000 |
| Catholics Percent: | 18.1 |
| Patron: | Nossa Senhora da Conceição |
| Parishes: | 22 |
| Priests: | 50 |
| Bishop: | Ernesto Maguengue |
The Roman Catholic Diocese of Inhambane (Latin: Inhambanian(us)) is a diocese located in the city of Inhambane in the ecclesiastical province of Maputo in Mozambique.
The Cathedral is Catedral da Nossa Senhora da Conceição (Cathedral of Our Lady of the Immaculate Conception) in Inhambane.