| Jurisdiction: | Diocese |
| Ho | |
| Latin: | Hoënsis |
| Country: |  Ghana |
| Metropolitan: | Accra |
| Rite: | Latin Rite |
| Area Km2: | 5,893 |
| Population: | 523,457 |
| Population As Of: | 2004 |
| Catholics: | 172,802 |
| Catholics Percent: | 33.0 |
| Bishop: | Emmanuel Fianu |
| Emeritus Bishops: | Francis Anani Kofi Lodonu |
| Cathedral: | Sacred Heart Cathedral, Ho-Bankoe |
The Roman Catholic Diocese of Ho (Latin: Hoën(sis)) is a diocese located in the city of Ho in the ecclesiastical province of Accra in Ghana.