| Jurisdiction: | Diocese |
| El Vigia-San Carlos del Zulia | |
| Latin: | Dioecesis Vigilantis-Sancti Caroli Zuliensis |
| Rite: | Latin Rite |
| Established: | 7 July 1994 (years ago) |
| Cathedral: | Our Lady of Perpetual Help Cathedral, El Vigia |
| Area Km2: | 8,100 |
| Population: | 368,176 |
| Population As Of: | 2004 |
| Catholics: | 357,130 |
| Catholics Percent: | 97.0 |
| Bishop: | Juan de Dios Peña Rojas |
| Map: | Diócesis de El Vigía-San Carlos.svg |
The Roman Catholic Diocese of El Vigia-San Carlos del Zulia (Latin: Dioecesis Dioecesis Vigilantis-Sancti Caroli Zuliensis) is a diocese located in the cities of El Vigía and San Carlos del Zulia in the Roman Catholic Archdiocese of Maracaibo in Venezuela.
On 7 July 1994 Blessed John Paul II established the Diocese of El Vigia–San Carlos del Zulia from the Diocese of Cabimas, Metropolitan Archdiocese of Maracaibo and Metropolitan Archdiocese of Mérida.