| Jurisdiction: | Diocese |
| Brejo | |
| Latin: | Dioecesis Breiensis |
| Country: |  Brazil |
| Province: | São Luís do Maranhão |
| Rite: | Latin Rite |
| Established: | 14 September 1971 (years ago) |
| Cathedral: | Catedral Nossa Senhora da Conceição |
| Area Km2: | 23,340 |
| Population: | 448,000 |
| Population As Of: | 2004 |
| Catholics: | 410,000 |
| Catholics Percent: | 91.5 |
| Bishop: | José Valdeci Santos Mendes |
| Emeritus Bishops: | Valter Carrijo, S.D.S. |
The Roman Catholic Diocese of Brejo (la|Dioecesis Breiensis) is a diocese located in the city of Brejo in the ecclesiastical province of São Luís do Maranhão in Brazil.