Roger Gosden Explained

Roger Gordon Gosden
Birth Date:23 September 1948
Birth Place:Ryde, Isle of Wight
Nationality:British & American
Fields:Physiology
Reproductive medicine
Workplaces:University of Cambridge
Duke University
Edinburgh Medical School
Leeds School of Medicine
McGill University Health Centre
Eastern Virginia Medical School
Weill Cornell Medical School
College of William & Mary
Alma Mater:University of Bristol
University of Cambridge
University of Edinburgh
Doctoral Advisor:Robert Edwards
Spouse:Lucinda Veeck Gosden
Partners:)-->
Thesis2 Title:Experimental and cytological studies of mammalian fertility and infertility with particular reference to the ageing ovary
Thesis2 Year:DSc 1989
Thesis1 Year:PhD 1974
Thesis1 Title:Reproductive senescence in female rodents
Thesis1 Url:http://ulmss-newton.lib.cam.ac.uk/vwebv/holdingsInfo?bibId=8858
Thesis2 Url:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.651650

Roger Gordon Gosden (born 23 September 1948) is a British-American physiologist in the field of female reproductive medicine. His scientific research focused on understanding the basic biology of development and senescence of ovaries in women, including mathematically modeling those processes. He did important translational research on ovarian tissue cryopreservation and transplantation.

Early life and education

Gosden was born on 23 September 1948 at Ryde on the Isle of Wight,[1] the son of Gordon Gosden and Peggy Gosden, née Butcher.[2] He went to Chislehurst and Sidcup Grammar School in Sidcup, Kent,[3] and then took a BSc from the University of Bristol in 1970.[1] He did post-graduate work under Robert Edwards at Darwin College, Cambridge, where he graduated PhD in 1974 with a thesis on Reproductive senescence in female rodents.[4] [5] [6]

Scientific career

Gosden was a lecturer in physiology at the University of Edinburgh Medical School from 1976 to 1994,[2] a professor of reproductive sciences at Leeds School of Medicine from 1994 to 1999,[1] and scientific director of reproductive biology at McGill University Health Centre from 1999 to 2001.[3] [7] His departure from the UK was the hook for an article in The Independent about a wave of scientists emigrating from the UK due to negative public opinion about scientists in the UK.[7] In 2001, Gosden became the director of scientific research at the Jones Institute for Reproductive Medicine at Eastern Virginia Medical School,[1] where he was named the Howard & Georgeanna Professor of Reproductive Medicine.[3] He left the Jones Institute in 2004 to become research director of reproductive biology at Weill Cornell Medicine, where his wife was on the faculty; part of the reason why Gosden left the institute was negative public opinion and criticism due to its creation in 2001 of an embryonic stem cell line, as was noted in a report in the journal, Science. He retired from research in 2010.

Gosden's research was focused on understanding, forecasting and treating infertility. His work focused on understanding basic biology around development and senescence of ovarian follicles and ovaries in women, including trying to mathematically model those processes, and he did important translational research on ovarian tissue cryopreservation and on ovary transplantation; his interests also extended to uterus transplantation.[8] In 1994, Gosden and colleagues announced that they had successfully restored fertility to and achieved two live births in sheep through ovarian tissue autotransplantation, one of which had been frozen then thawed.[9] In collaboration with Sherman Silber, this technique was later extended to women using tissue or the entire ovary transplanted from an identical twin.[10] [11] [12] [13], there had been 86 live-births and were 9 on-going pregnancies directly as a result of these types of ovarian tissue transplantation.[14]

Gosden was a scientific advisor to Celmatix, Inc., which was founded by his former student.[15] [16] He spoke out against the controversial claims made by OvaScience, a company founded in 2012, that it could help older women conceive using putative oogonial stem cells.[17]

Personal life

Gosden married Carole Ann Walsh in 1971 and they had two sons before their divorce in 2003.[1] [3] In 2004 he married Lucinda Veeck, whom he had met at the Jones Institute in Norfolk when she was working there.[18] [19] [20] In the same year he moved to New York to work at Weill Cornell Medicine, where Veeck was director of clinical embryology.[21]

In 2010, they both moved to Williamsburg, Virginia, where they run an independent publishing company, Jamestowne Bookworks,[22] which Gosden opened as outlet for his own works, to allow him to control his own works after a life of assigning copyright to biomedical publishers, and to publish other people's work that interested him.[23]

Honours and lectures

Books

Notes and References

  1. Book: Peacock, Scot. Contemporary Authors, New Revision Series. 2004. Gale. 978-0-7876-9201-8. Detroit, Michigan. glish. 527378529. 6 February 2017. Encyclopedia.com.
  2. Book: Lumley, Elizabeth. The Canadian Who's Who. 2002. University of Toronto Press. 978-0-8020-4970-4. 514.
  3. Book: The International Who's Who 2004. 2003. Europa Publications Limited. 978-1-85743-217-6. Sleeman. Elizabeth. London. 491652781. Neale. Alison. Robinson. Kate.
  4. News: New York alumni gathering. 2007. The Darwinian. 2017-02-06. Prentice. Andrew. Issuu.com. Smith. Sophia. Jebb. Hawkes. Richard. Dean. 2.
  5. Reproductive senescence in female rodents. Gosden. R.G.. University of Cambridge Department of Physiology. 1974-05-21.
  6. Johnson. MH. Robert Edwards: the path to IVF. Reproductive Biomedicine Online. August 2011. 23. 2. 245–62. 21680248. 3171154. 10.1016/j.rbmo.2011.04.010.
  7. News: Focus: The Brain Drain: Medical stars pack their bags. Dobson. Roger. 1999-09-26. The Independent. 2017-02-11. en-GB.
  8. Gosden. RG. Ovary and uterus transplantation.. Reproduction. December 2008. 136. 6. 671–80. 10.1530/REP-08-0099. 18728099. free.
  9. Prasath. Ethiraj B.. 2008-01-01. Ovarian tissue cryopreservation: An update. Journal of Human Reproductive Sciences. 1. 2. 50–55. 2700672. 19562046. 10.4103/0974-1208.44111 . free .
  10. Silber. S. J.. 2012-02-01. Ovary cryopreservation and transplantation for fertility preservation. Molecular Human Reproduction. 18. 2. 59–67. 10.1093/molehr/gar082. 22205727. free.
  11. Silber. S.J.. Grudzinskas . Gedis. Gosden . R.G. . 2 . 2008-12-11. Successful pregnancy after microsurgical transplantation of an intact ovary. The New England Journal of Medicine. 359. 24. 2617–2618. 10.1056/NEJMc0804321. 19073987. 74857297. free.
  12. News: Fertility: stop all the clocks. Lambert. Victoria. 2009-11-26. Telegraph.co.uk. 2017-02-11. https://archive.today/20170211062805/http://www.telegraph.co.uk/women/womens-health/6651648/Fertility-stop-all-the-clocks.html. 11 February 2017. live. dmy-all.
  13. News: Dr. Sherman Silber Takes His Reproductive Technology to China. Cooperman. Jeannette. 2012-09-07. St. Louis Magazine. 2017-02-11. https://archive.today/20170211062541/https://www.stlmag.com/Dr-Sherman-Silber-Takes-His-Reproductive-Technology-to-China/. 11 February 2017. live. en-US. dmy-all.
  14. Jensen. A. K.. Macklon. K. T.. Fedder. J.. Ernst. E.. Humaidan. P.. Andersen. C. Y.. 2016-12-27. 86 successful births and 9 ongoing pregnancies worldwide in women transplanted with frozen-thawed ovarian tissue: focus on birth and perinatal outcome in 40 of these children. Journal of Assisted Reproduction and Genetics. 34. 3. 325–336. 10.1007/s10815-016-0843-9. 28028773. 5360679.
  15. Mollory. Chris. Charlie. Grebenstein. David. Seemungal. Krasilnikov. Darya. 2016. Digital Healthcare - RSA Talent Equity Report. RSA Group. 23. 2017-02-08. 2.
  16. Web site: Celmatix, Inc. - Relationship Science. Relationshipscience.com. https://archive.today/20170208195503/http://relationshipscience.com/celmatix-inc-o235658. 8 February 2017. live. 2017-02-08. dmy-all.
  17. News: Boyd. Roddy. Irreproducible Results, Inc.. Southern Investigative Reporting Foundation. 6 April 2015.
  18. News: Simpson. Elizabeth. For in vitro pioneer, even at 103, the work never ends. Virginian-Pilot. 1 December 2014.
  19. Book: Mundy, Liza. Everything Conceivable. 2007-04-24. Knopf Doubleday Publishing Group. 978-0-307-26727-6.
  20. Garcia. Jairo. Veeck. Lucinda. Acosta. Anibal. Andrews. Mason C.. Jones. Georgeanna Seegar. Jones. Howard W.. Mantzavinos. Themis. Mayer. Jacob. McDowell. Jeanne. 2. 1984. In vitro fertilization in Norfolk, Virginia, 1980–1983. Journal of in Vitro Fertilization and Embryo Transfer. 1. 1. 24–28. 10.1007/BF01129616. 6336088. 26041741. 0740-7769.
  21. Science. American Association for the Advancement of. Random Samples. Science. 3 September 2004. 305. 5689. 1398. 0036-8075.
  22. News: Simpson. Elizabeth. Father of in-vitro fertilization delivers final story of medicine, love. Virginian-Pilot. 8 October 2015.
  23. Phelps. Linda Landreth. Dr. Roger Gosden: Scientist and Writer. Williamsburgh's Next Door Neighbors. March 2015. 9. 3. 21–23.
  24. News: Past Awards - Society for Reproduction and Fertility. Society for Reproduction and Fertility. 2017-02-06. https://archive.today/20170206184629/http://srf-reproduction.org/grants-awards/awards/past-awards/. 6 February 2017. live. en-GB. dmy-all.
  25. News: Newsletter - Autumn 2013. British Fertility Society. Bioscientifica Ltd. Campbell. Trudi. 5, 7. 2045-6891.
  26. Web site: XVth Development and Function of Reproductive Organs International Conference. University of St Andrews. https://archive.today/20170206224510/https://risweb.st-andrews.ac.uk/portal/en/activities/xvth-development-and-function-of-reproductive-organs-international-conference(923257f7-ec8e-4cc4-b6e9-a3185830a2ea).html. 6 February 2017. live. 2017-02-06. dmy-all.
  27. Hillier. P. S. G.. 2012-02-01. Modern methods of fertility preservation: a tribute to Roger Gosden. Molecular Human Reproduction. 18. 2. 57–58. 10.1093/molehr/gas003. 22287563. free.
  28. Web site: Board Of Directors. Bronchart. Rudy Lechantre and Gregory. International Society for Fertility Preservation. https://archive.today/20170206225122/http://www.isfp-fertility.org/about-isfp/board-of-directors/. 6 February 2017. live. 2017-02-06. dmy-all.

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