| Honorific-Prefix: | Most Reverend |
| Rodrigo de Luna | |
| Archbishop of Santiago de Compostela | |
| Church: | Catholic Church |
| Archdiocese: | Archdiocese of Santiago de Compostela |
| Term: | 1449–1460 |
| Predecessor: | Álvaro Núñez de Isorna |
| Successor: | Alonso de Fonseca y Acevedo |
| Death Date: | 1460 |
| Death Place: | Santiago de Compostela, Spain |
Rodrigo de Luna (died 1460) was a Roman Catholic prelate who served as Archbishop of Santiago de Compostela (1449–1460).[1]
On 7 April 1449, Rodrigo de Luna was appointed during the papacy of Pope Nicholas V as Archbishop of Santiago de Compostela. He served as Archbishop of Santiago de Compostela until his death in 1460. While bishop, he was the principal consecrator of Pedro González de Mendoza, Bishop of Calahorra y La Calzada (1454).