| Robert Martin Glaeser | |
| Alma Mater: | University of California, Berkeley University of Wisconsin – Madison |
| Birth Date: | 20 July 1937 |
| Birth Place: | Kenosha, Wisconsin, U.S. |
| Website: | http://mcb.berkeley.edu/faculty/all/glaeserr |
| Known For: | development of cryo-EM |
Robert Martin Glaeser (born July 20, 1937) is an American biochemist. He is a professor emeritus of Biochemistry, Biophysics and Structural Biology at the University of California, Berkeley and a faculty scientist at Lawrence Berkeley National Laboratory, in Berkeley, California, US. His main research area is electron diffraction and membrane models.
Glaeser is known[1] for his pioneering work in cryogenic electron microscopy (cryo-EM), where he established how radiation damage was a limiting factor for imaging resolution[2] and how freezing hydrated specimens allowed for more tolerance to radiation damage.[3] He also pushed electron imaging microscopy resolution and contrast by studying the effect of beam-induced movement on the resolution[4] and developed methods for weak-phase imaging.[5]
Glaeser studied at the University of Wisconsin – Madison (B.A. 1959) and the University of California, Berkeley (Ph.D. 1964). He was then a postdoc at the University of Oxford (1963/64) and University of Chicago (1964/65). In 1988/89 he was a visiting scientist at the Max Planck Institute for Biochemistry (MPIB) in Martinsried near Munich, and later a professor at the University of California, Berkeley.