| Country: | IRN |
| Type: | road |
| Route: | 81 |
| Terminus A: | Sari, Mazandaran |
| Terminus B: | Near Kharanaq, Yazd |
| Length Km: | 650 |
| Provinces: | Mazandaran, Semnan, Isfahan, Yazd |
| Junction: | |
| Map: | Road 81 in Iran.jpg |
Road 81 is a road in central Iran. It starts from Sari, goes to Damghan and passes Dasht-e Kavir and Road 62 and Khur and ends at Yazd-Mashhad Road.[1]