Ro05-4082 Explained

Ro05-4082 (N-methylclonazepam, ID-690) is a benzodiazepine derivative developed in the 1970s. It has sedative and hypnotic properties, and has around the same potency as clonazepam itself.^[1] It was never introduced into clinical use. It is a structural isomer of meclonazepam (3-methylclonazepam), and similarly has been sold as a designer drug, first being identified in Sweden in 2017.^[2]

See also

• Clonazolam
• Cloniprazepam
• Flunitrazepam

Notes and References

1. Fukuda H, Kudo Y, Ono H, Togari A, Tanaka Y . [Pharmacological study on 5-(o-chlorophenyl)-1-methyl-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one (ID-690), with special reference to the effects on motor systems] . Japanese . Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica . 73 . 1 . 123–34 . January 1977 . 558942 . 10.1254/fpj.73.123 . free .
2. Web site: Novel Benzodiazepines. A review of the evidence of use and harms of Novel Benzodiazepines. . Advisory Council on the Misuse of Drugs . April 2020 .