Richard Gilbertson Explained

Richard Gilbertson
Birth Name:Richard James Gilbertson
Workplaces:Cancer Research UK Cambridge Institute, University of CambridgeSt. Jude Children's Research HospitalNewcastle University
Alma Mater:Newcastle University (B.Med.Sci, MB BS, PhD)
Thesis Year:1998
Awards:Fellow of the Royal Society, Fellow of the Academy of Medical Sciences, Fellow of the Royal College of Physicians
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Professor Richard James Gilbertson is a Senior Group Leader at the Cancer Research UK Cambridge Institute, University of Cambridge.[1] He is the Li Ka Shing Chair of Oncology,[2] and Director of the CRUK Cambridge Major Centre[3] and the Children's Brain Tumour Centre of Excellence.[4]

Education

Gilbertson attended Medical School at Newcastle University,[5] graduating with Bachelor of Medical Science, Bachelor of Medicine, Bachelor of Surgery degrees in 1992.[6] He went on to complete his PhD in 1998 as an MRC Clinical Training Fellow with Professors Andrew Pearson and John Lunec before becoming an MRC Clinical Scientist in 1998.[7]

Career and research

Gilbertson's research focuses on understanding the link between normal development and the origins of cancer, with a particular focus on children's brain tumours. He has shown that clinically distinct subtypes of childhood medulloblastoma and ependymoma arise within different lineages of developing brain and are driven by distinct mutations in their DNA.[8] [9] [10] [11] His work has also shown that a combination of stem cell mutagenesis and extrinsic factors that enhance the proliferation of progenitor cell populations across multiple organs ultimately determines organ cancer risk.[12] [13]

In 2000, Gilbertson joined the St Jude Children's Research Hospital in Memphis, Tennessee.[14] There, he became the founding director of the Molecular Clinical Trials Core and the co-leader of the Neurobiology and Brain Tumor Program.[15] In 2011, he was named executive vice president of St. Jude and director of its Comprehensive Cancer Centre.[16] [17] In 2014 he was also appointed Scientific Director of St. Jude Children's Research Hospital.

In 2015, he returned to the UK as the Li Ka Shing Chair of Oncology, head of the Department of Oncology, senior group leader at the Cancer Research UK Cambridge Institute at the University of Cambridge and Director of the CRUK Cambridge Major Centre.[18]

He was elected: Fellow of the Academy of Medical Sciences (FMedSci) in 2017; Fellow of the European Academy of Cancer Sciences in 2017;[19] and Fellow of the Royal Society of London (FRS) in 2022.[20] His certificate for election to Fellow of the Royal Society reads:

Awards and honours

Notes and References

  1. Web site: Gilbertson Group. Cancer Research UK Cambridge Institute. en-GB. 2019-06-05. 2019-06-28. https://web.archive.org/web/20190628120438/https://www.cruk.cam.ac.uk/research-groups/gilbertson-group. live.
  2. Web site: Childhood brain tumour expert to lead Cambridge Cancer Centre. 2015-03-26. University of Cambridge. en. 2019-06-04. 2020-10-22. https://web.archive.org/web/20201022121601/https://www.cam.ac.uk/news/childhood-brain-tumour-expert-to-lead-cambridge-cancer-centre. live.
  3. News: Cancer centres receive £15m boost. 2015-06-26. BBC News. 2019-06-04. en-GB. 2016-11-29. https://web.archive.org/web/20161129191729/http://www.bbc.com/news/uk-england-33273226. live.
  4. News: Brain tumour research to get £18m injection. Davis. Nicola. 2018-05-01. The Guardian. 2019-06-04. en-GB. 0261-3077. 2019-09-03. https://web.archive.org/web/20190903135250/https://www.theguardian.com/science/2018/may/01/brain-tumour-research-to-get-18m-injection. live.
  5. Web site: Man on a mission to beat cancer. 2016-11-14. University of Cambridge. en. 2019-06-04. 2018-07-31. https://web.archive.org/web/20180731111210/https://www.cam.ac.uk/research/features/man-on-a-mission-to-beat-cancer. live.
  6. Web site: Richard J. Gilbertson. www.sontagfoundation.org. 2019-06-05. 2019-10-21. https://web.archive.org/web/20191021142424/http://www.sontagfoundation.org/recipients/richard-j-gilbertson/. live.
  7. Web site: A Conversation with Richard J. Gilbertson, MD, PhD . live . https://web.archive.org/web/20200814171711/https://ascopost.com/issues/november-1-2011/a-conversation-with-richard-j-gilbertson-md-phd/ . 2020-08-14 . 2019-06-05 . The ASCO Post.
  8. Gajjar. Amar. Pfister. Stefan M.. Taylor. Michael D.. Gilbertson. Richard J.. 2014-11-15. Molecular insights into pediatric brain tumors have the potential to transform therapy. Clinical Cancer Research. 20. 22. 5630–5640. 10.1158/1078-0432.CCR-14-0833. 1078-0432. 4234174. 25398846.
  9. Web site: Expert Opinion – Professor Richard Gilbertson talks children's cancers. Cancer Research UK - Science blog. 26 November 2015. 2019-06-05. 2019-11-13. https://web.archive.org/web/20191113223710/https://scienceblog.cancerresearchuk.org/2015/11/26/expert-opinion-professor-richard-gilbertson-talks-childrens-cancers/. live.
  10. Gibson . P . 2010 . Subtypes of medulloblastoma have distinct developmental origins . Nature . 468 . 7327 . 1095–1099. 10.1038/nature09587 . 21150899 . 3059767 .
  11. Parker . M . 2014 . C11orf95-RELA fusions drive oncogenic NF-kappaB signalling in ependymoma . Nature . 506 . 7489 . 451–455. 10.1038/nature13109 . 24553141 . 4050669 .
  12. Zhu. Liqin. Finkelstein. David. Gao. Culian. Shi. Lei. Wang. Yongdong. López-Terrada. Dolores. Wang. Kasper. Utley. Sarah. Pounds. Stanley. 2016-08-25. Multi-organ Mapping of Cancer Risk. Cell. 166. 5. 1132–1146.e7. 10.1016/j.cell.2016.07.045. 27565343. 5067024. 0092-8674.
  13. 2016-09-07. Cancer: 'Perfect storm' of cancer risk. Nature. en. 537. 7619. 140. 10.1038/537140c. 27604915. 1476-4687. 2016Natur.537S.140.. free.
  14. Web site: St. Jude Children's Research Hospital scientific director announces resignation. www.stjude.org. en. 2019-06-05. 2020-09-27. https://web.archive.org/web/20200927075830/https://www.stjude.org/media-resources/news-releases/2015-medicine-science-news/scientific-director-announces-resignation.html. live.
  15. Web site: Professor Richard Gilbertson. Cambridge Biomedical Research Centre. 2019-06-05. 2019-05-10. https://web.archive.org/web/20190510161918/https://cambridgebrc.nihr.ac.uk/research/cancer/contact-details/. live.
  16. Web site: British Cancer Researcher on Why He Moved to the U.S.. Bartlett. James. BBC America. en-US. 2019-06-04. 2022-05-31. https://web.archive.org/web/20220531121616/https://www.bbcamerica.com/favicon.ico. live.
  17. Web site: Coming home to the UK: an interview with Richard Gilbertson. 2016-07-20. Cancer Research UK. en. 2019-06-04. 2017-12-17. https://web.archive.org/web/20171217143921/http://www.cancerresearchuk.org/funding-for-researchers/research-features/2016-08-10-researcher-annual-publication-richard-gilbertson-interview. live.
  18. News: Professor Richard Gilbertson appointed Head of Department - Department of Oncology. 2019-06-05. en. 2022-05-31. https://web.archive.org/web/20220531121607/https://www.oncology.cam.ac.uk/news-events/gilbertson-head. live.
  19. Web site: Fellows European Academy of Cancer Sciences . 2022-06-13 . www.europeancanceracademy.eu.
  20. Web site: Outstanding scientists elected as Fellows and Foreign Members of the Royal Society Royal Society . 2022-06-13 . royalsociety.org.
  21. Web site: Previous Schweisguth Prize Winners. Société Internationale d’Oncologie Pédiatrique. 2019-06-04. 2020-08-09. https://web.archive.org/web/20200809150418/https://siop-online.org/previous-schweisguth-prize-winners/. live.
  22. Web site: Dr Simon Newell Early Career Investigator of the Year (Sparks) award. RCPCH. en. 2019-06-04. 2022-05-31. https://web.archive.org/web/20220531121559/https://www.rcpch.ac.uk/education-careers/fellowships-and-prizes/dr-simon-newell-early-independent-researcher-award. live.
  23. Web site: British Paediatric Neurology Association. bpna.org.uk. 2019-06-04. 2020-08-08. https://web.archive.org/web/20200808234655/https://bpna.org.uk/?page=mackeith-prize-lecturers. live.
  24. Gutmann. David H.. Gilbertson. Richard J.. 2007-06-15. Tumorigenesis in the Brain: Location, Location, Location. Cancer Research. en. 67. 12. 5579–5582. 10.1158/0008-5472.CAN-07-0760. 0008-5472. 17575119. free. 2019-06-11. 2018-06-02. https://web.archive.org/web/20180602184416/http://cancerres.aacrjournals.org/content/67/12/5579. live.
  25. Web site: Honors & awards. www.stjude.org. en. 2019-06-04. 2019-05-03. https://web.archive.org/web/20190503145859/https://www.stjude.org/about-st-jude/honors-and-awards.html. live.
  26. Web site: ALSF CORD Fund History. 2019-03-07. Alex's Lemonade Stand Foundation for Childhood Cancer. en. 2019-06-06. 2015-03-18. https://web.archive.org/web/20150318115538/http://alexslemonade.org/campaign/alsf-cord-fund/alsf-cord-fund-history. live.
  27. https://www.aans.org/-/media/Images/AANS/Past-Meetings/an11/AN11_Program_Guide_Final.ashx?la=en&hash=AACA6128DA1F494A0F7EFEA0953CC511451BA1CB "AANS Programme Guide 2011"
  28. Web site: The American Society for Clinical Investigation. en-US. 2019-06-04. 2022-05-31. https://web.archive.org/web/20220531121600/https://the-asci.org/controllers/asci/AsciProfileController.php?pid=500987. live.
  29. Web site: Professor Richard Gilbertson . live . https://web.archive.org/web/20220531121607/https://acmedsci.ac.uk/fellows/fellows-directory/ordinary-fellows/fellow/Professor-Richard-Gilbertson-0023663 . 2022-05-31 . 2019-06-04 . The Academy of Medical Sciences.
  30. Web site: Richard Gilbertson . 2022-05-11 . The Royal Society . 2022-05-11 . https://web.archive.org/web/20220511202204/https://royalsociety.org/people/richard-gilbertson-35830/ . live .
  31. Web site: Richard Gilbertson Named 2022 Society of Memorial Sloan Kettering Prize Recipient for Contributions in Pediatric Oncology Memorial Sloan Kettering Cancer Center . 2022-06-13 . www.mskcc.org . en.

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