Richard Lenski Explained

Richard Eimer Lenski
Birth Date:13 August 1956
Fields:Evolutionary biology Experimental evolution
Workplaces:Michigan State University
University of California, Irvine
Alma Mater:University of North Carolina, Chapel Hill
Oberlin College
Thesis Title:Effects of competition and disturbance on ground beetle populations
Thesis Url:https://www.worldcat.org/oclc/9150582
Thesis Year:1982
Doctoral Advisor:Nelson Hairston
Academic Advisors:Bruce Levin (Postdoctoral Mentor)
Doctoral Students:Paul E. Turner
Zachary Blount
Known For:E. coli long-term evolution experiment
Awards:NCSE Friend of Darwin Award [1]
Sewall Wright Award
MacArthur Fellowship
Guggenheim Fellowship [2]

Richard Eimer Lenski (born August 13, 1956) is an American evolutionary biologist,[3] a Hannah Distinguished Professor of Microbial Ecology, Genetics and Evolution, and Evolution of Pathogen Virulence at Michigan State University. He is a member of the National Academy of Sciences and a MacArthur Fellow. Lenski is best known for his still ongoing -year-old long-term E. coli evolution experiment, which has been instrumental in understanding the core processes of evolution, including mutation rates,[4] clonal interference,[5] antibiotic resistance,[6] the evolution of novel traits,[7] and speciation.[8] He is also well known for his pioneering work in studying evolution digitally using self-replicating organisms called Avida.

Early life

Richard E. Lenski is the son of sociologist Gerhard Lenski and poet Jean Lenski (Cappelmann).[9] He is also the great-nephew of children's author Lois Lenski and the great-grandson of Lutheran commentator Richard C. H. Lenski. He earned his BA from Oberlin College in 1976, and his PhD from the University of North Carolina in 1982.[10]

Career

Lenski won a Guggenheim Fellowship in 1991 and a MacArthur Fellowship in 1996, and in 2006 he was elected to the United States National Academy of Sciences.[11]

Lenski is a fellow at the American Academy of Microbiology and the American Academy of Arts and Sciences and holds the office Hannah Distinguished Professor of microbial ecology at Michigan State University.

On February 17, 2010, he co-founded the NSF Science and Technology Center for the Study of Evolution in Action, known as the BEACON Center.[1]

He was elected to the American Philosophical Society in 2018.[12]

Lenski was the recipient of the 2021 Lifetime Achievement Award from the Society for the Study of Evolution.[13]

E. coli experiment

See main article: E. coli long-term evolution experiment.

The E. coli long-term evolution experiment is an ongoing study in experimental evolution led by Richard Lenski that has been tracking genetic changes in 12 initially identical populations of asexual Escherichia coli bacteria since 24 February 1988.[14] The populations reached the milestone of 75,000 generations in 2022.[15]

Since the experiment's inception, Lenski and his colleagues have reported a wide array of genetic changes; some evolutionary adaptations have occurred in all 12 populations, while others have only appeared in one or a few populations. One particularly striking adaptation was the evolution of a strain of E. coli that was able to use citrate as a carbon source in an aerobic environment.[16] A defining characteristic of E. coli is its inability to use citrate as an energy source under oxic conditions.[17]

Avida simulation

Richard Lenski, Charles Ofria, et al. at Michigan State University developed an artificial life computer program with the ability to detail the evolution of complex systems. The system uses values set to determine random mutations and allows for the effect of natural selection to conserve beneficial traits. The program was dubbed Avida and starts with an artificial petri dish where organisms reproduce and perform mathematical calculations to acquire rewards of more computer time for replication. The program randomly adds mutations to copies of the artificial organisms to allow for natural selection. As the artificial life reproduced, different lines adapted and evolved depending on their set environments. The beneficial side to the program is that it parallels that of real life at rapid speeds.[18] [19] [20] [21]

Media

In August 2013, having been inspired by a presentation by Titus Brown on the role of social media in science, Lenski began blogging at Telliamed Revisited and tweeting as @RELenski.[22]

Lenski's research has received considerable attention, including lengthy discussion in Carl Zimmer's book on E. coli, Microcosm, and in Richard Dawkins' book on the evidence for evolution, The Greatest Show on Earth. Included in Dawkins' discussion was a description of the dialog Lenski had in 2008 with Andrew Schlafly, creator of Conservapedia, which Schlafly initiated as a reaction to reports of Lenski's description of the evolution of aerobic citrate usage in one of the long-term evolution experiment populations. These same findings were later cited by the creationist Ken Ham in a debate over evolution with Bill Nye. Lenski strongly criticized Ham's citation of his work and the conclusions Ham drew from it.[23]

External links

Notes and References

  1. Web site: MSU's Richard Lenski wins 2017 Friend of Darwin award.
  2. Web site: John Simon Guggenheim Foundation | Richard E. Lenski.
  3. News: Richard Lenski . . 2008 . 2008-09-17.
  4. Tenaillon. Olivier. Barrick. Jeffrey E.. Ribeck. Noah. Deatherage. Daniel E.. Blanchard. Jeffrey L.. Dasgupta. Aurko. Wu. Gabriel C.. Wielgoss. Sébastien. Cruveiller. Stéphane. 2016-08-11. Tempo and mode of genome evolution in a 50,000-generation experiment. Nature. en. 536. 7615. 165–170. 10.1038/nature18959. 0028-0836. 4988878. 27479321. 2016Natur.536..165T.
  5. Maddamsetti. Rohan. Lenski. Richard E.. Barrick. Jeffrey E.. 2015-06-01. Adaptation, Clonal Interference, and Frequency-Dependent Interactions in a Long-Term Evolution Experiment with Escherichia coli. Genetics. en. 200. 2. 619–631. 10.1534/genetics.115.176677. 0016-6731. 4492384. 25911659.
  6. Lenski. R. E.. 1998-12-01. Bacterial evolution and the cost of antibiotic resistance. International Microbiology. 1. 4. 265–270. 1139-6709. 10943373.
  7. Blount. Zachary D.. Borland. Christina Z.. Lenski. Richard E.. 2008-06-10. Historical contingency and the evolution of a key innovation in an experimental population of Escherichia coli. Proceedings of the National Academy of Sciences. en. 105. 23. 7899–7906. 10.1073/pnas.0803151105. 0027-8424. 2430337. 18524956. 2008PNAS..105.7899B. free.
  8. Meyer. Justin R.. Dobias. Devin T.. Medina. Sarah J.. Servilio. Lisa. Gupta. Animesh. Lenski. Richard E.. 2016-11-24. Ecological speciation of bacteriophage lambda in allopatry and sympatry. Science. 354. 6317. en. 1301–1304. 10.1126/science.aai8446. 0036-8075. 27884940. 2016Sci...354.1301M. free.
  9. Richard Lenski . relenski. 501149475541618688 . August 17, 2014 . Photo of Richard Lenski and Gerhard Lenski for the father's 90th birthday . August 18, 2014 .
  10. Book: Campbell. Neil A.. Reece. Jane B.. Biology. registration. 7. 538–539. 978-0-8053-7146-8. 2005. Pearson, Benjamin Cummings .
  11. United States National Academy of Sciences member list, "Member directory", Richard E. Lenski , 2006
  12. Web site: Election of New Members at the 2018 Spring Meeting.
  13. Web site: Society for the Study of Evolution. 2021-07-04. www.evolutionsociety.org. en.
  14. Web site: Richard E. . Lenski . Source of founding strain . Michigan State University . Richard E. Lenski Homepage . 2000 . 2008-06-18 . 2018-05-31 . https://web.archive.org/web/20180531192907/http://myxo.css.msu.edu/ecoli/strainsource.html . dead .
  15. Lenski . Richard . February 15, 2023 . Revisiting the Design of the Long-Term Evolution Experiment with Escherichia coli . Journal of Molecular Evolution . 91 . 1. 241–253 . 10.1007/s00239-023-10095-3 . 36790511 . 2023JMolE..91..241L . 256869639 .
  16. 7899–906 . 10.1073/pnas.0803151105 . Historical contingency and the evolution of a key innovation in an experimental population of Escherichia coli . 2008 . Blount . Zachary D. . Borland . Christina Z. . Lenski . Richard E. . Proceedings of the National Academy of Sciences . 105 . 23 . 25462703 . 18524956 . 2008PNAS..105.7899B . 2430337. free .
  17. Blount . Zachary . Borland . Christina . Lenski . Richard . June 10, 2008 . Historical contingency and the evolution of a key innovation in an experimental population of Escherichia coli . PNAS . 105 . 23 . 7899–7906. 10.1073/pnas.0803151105 . 18524956 . 2430337 . 2008PNAS..105.7899B . free .
  18. Lenski. R. E.. Ofria. C.. Pennock. R. T.. Adami. C.. 2003. Charles Ofria. Robert T. Pennock. Chris Adami. The evolutionary origin of complex features. Nature. 423. 139–144. 2003Natur.423..139L. 10.1038/nature01568. 12736677. 6936. 4401833. 2013-08-20. 2021-01-21. https://web.archive.org/web/20210121232710/http://myxo.css.msu.edu/papers/nature2003/Nature03_Complex.pdf. dead.
  19. Web site: Digital organisms used to confirm evolutionary process . 2011-03-21 . American Association for the Advancement of Science .
  20. Web site: Artificial life experiments show how complex functions can evolve . 2011-03-21 . American Association for the Advancement of Science .
  21. Evolution of digital organisms at high mutation rates leads to survival of the flattest. Richard E. Lenski . Charles Ofria . Claus O. Wilke . Jia Lan Wang . Christoph Adami . amp . Nature. 2001-07-19. 412. 331–3. 10.1038/35085569. 6844 . 11460163. 2001Natur.412..331W . 1482925 .
  22. Web site: Welcome to Telliamed Revisited. Richard Lenski. August 19, 2013.
  23. https://telliamedrevisited.wordpress.com/2014/02/05/ham-on-nye-debate-follow-up-1/, https://telliamedrevisited.wordpress.com/2014/02/06/ham-on-nye-debate-follow-up-2/, https://telliamedrevisited.wordpress.com/2014/02/07/zachary-blount-on-ham-on-nye-debate-follow-up-3/