Richard C. Mulligan Explained

Richard C. Mulligan
Fields:Gene Therapy
Workplaces:Massachusetts Institute of Technology, Harvard Medical School, Sana Biotechnology
Alma Mater:Massachusetts Institute of Technology, Stanford University
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Doctoral Advisor:Paul Berg
Academic Advisors:Alexander Rich, David Baltimore, Phillip Allen Sharp
Notable Students:James Wilson (scientist), Constance Cepko, David Sanders (biologist), Roger D. Cone
Known For:Gene Therapy
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Richard C. Mulligan (born 1954) is an American scientist who is the Mallinckrodt Professor of Genetics at Harvard Medical School,[1] [2] [3] the Director of the Harvard Gene Therapy Initiative and a visiting scientist at the Koch Institute for Integrative Cancer Research at the Massachusetts Institute of Technology.[4] He is also the head of SanaX at Sana Biotechnology.

Research and career

Mulligan started his career in gene therapy as an undergraduate in biology in Alexander Rich's lab at MIT and was involved with early work controlling gene expression using SV40. He would earn his PhD in biochemistry at Stanford University in 1980 working with Paul Berg to develop viral vectors to express human and bacterial genes.[5] [6] He would then do his postdoctoral training at the Center for Cancer Research at MIT with David Baltimore and Phillip Sharp. He would join the faculty of molecular biology and was a member of the Whitehead Institute for Biomedical Research.[7] During that time, he was a founding member of the Recombinant DNA Advisory Committee (RAC). In 1996, he joined Children's Hospital and Harvard to become the director of the Harvard Gene Therapy Initiative and an investigator of the Howard Hughes Medical Institute.[8]

Mulligan is an active investor as the founding partner and senior managing director of Sarissa Capital Management from 2013 to 2016 along with Alex Denner when they worked together with Carl Icahn.[9] He would then join Icahn Capital as a portfolio manager in 2017. He serves as Director of Enzon Pharmaceuticals, Inc.,[10] and Biogen Idec, Inc.[11] [12]

Awards

Works

Notes and References

  1. Web site: Richard C. Mulligan, Ph.D. | HMS Department of Genetics. May 2016 . genetics.med.harvard.edu. 2016-06-21.
  2. Web site: Harvard BBS PHD Program.
  3. Web site: Richard C. Mulligan, Ph.D. - DF/HCC. dfhcc.harvard.edu. 2016-06-21. 2015-05-31. https://web.archive.org/web/20150531065404/http://www.dfhcc.harvard.edu/membership/profile/member/689/0/. dead.
  4. Web site: Richard C. Mulligan. people.forbes.com . https://web.archive.org/web/20110804174929/https://people.forbes.com/profile/richard-c-mulligan/43072 . August 4, 2011 . 2016-06-21.
  5. Mulligan . R. C. . Berg . P. . Expression of a Bacterial Gene in Mammalian Cells . Science . 19 September 1980 . 209 . 4463 . 1422–1427 . 10.1126/science.6251549. 6251549 . 1980Sci...209.1422M .
  6. Mulligan . Richard C. . Howard . Bruce H. . Berg . Paul . Synthesis of rabbit β-globin in cultured monkey kidney cells following infection with a SV40 β-globin recombinant genome . Nature . January 1979 . 277 . 5692 . 108–114 . 10.1038/277108a0. 215915 . 1979Natur.277..108M . 4257109 .
  7. Mulligan . Richard C. . Development of Gene Transfer Technology . Human Gene Therapy . December 2014 . 25 . 12 . 995–1002 . 10.1089/hum.2014.2543. 25513845 .
  8. Dickman . S . Richard Mulligan: from skeptic to true believer. . Current Biology . 1 October 1997 . 7 . 10 . R601-2 . 10.1016/s0960-9822(06)00308-3 . 9382777. 9998648 . free .
  9. News: Denner said to start activist health-care hedge fund . Connecticut Post . 11 April 2013.
  10. Web site: Enzon. enzon.com. 2016-06-21.
  11. Web site: Business Briefing / Biotechnology - latimes. 4 June 2009 . Los Angeles Times. 2016-06-21.
  12. News: Writer . GEN Staff . Icahn Names Gene Transfer Pioneer as Portfolio Manager . GEN - Genetic Engineering and Biotechnology News . 3 March 2017.
  13. Web site: Searle Scholars Program : Richard C. Mulligan (1983). searlescholars.net. 2016-06-21.
  14. News: Mulligan receives new award . MIT News Massachusetts Institute of Technology . 2 June 1993 . en.