Ribosomal protein L19 leader explained
| L19-Flavobacteria |
| Symbol: | L19-Flavobacteria |
| Rfam: | RF03130 |
| Rna Type: | Cis-reg
- leader
|
L19 Ribosomal protein leaders[1] are part of the ribosome biogenesis. They are used as an autoregulatory mechanism to control the concentration of ribosomal proteins L19, and are located in the 5′ untranslated regions of mRNAs encoding ribosomal protein L19 (rplS).L19 ribosomal protein leaders have been bioinformatically predicted in B. subtilis and other low-GC Gram-positive bacteria in the phylum Bacillota.[2] More examples that share a similar structure were predicted in Flavobacteria,[3] also using bioinformatic approaches.
See also
Notes and References
- Book: Zengel JM, Lindahl L . Diverse mechanisms for regulating ribosomal protein synthesis in Escherichia coli . 47 . 331–370 . 1994 . 7517053 . 10.1016/S0079-6603(08)60256-1 . 978-0-12-540047-3 . Progress in Nucleic Acid Research and Molecular Biology .
- Yao . Z . Barrick . J . Weinberg . Z . Neph . S . Breaker . R . Tompa . M . Ruzzo . WL . A computational pipeline for high-throughput discovery of cis-regulatory noncoding RNA in prokaryotes . PLOS Computational Biology . 3 . 7 . 2007 . e126 . 10.1371/journal.pcbi.0030126 . 17616982 . 1913097 . 2007PLSCB...3..126Y . free .
- Eckert . I . Weinberg . Z . Discovery of 20 novel ribosomal leader candidates in bacteria and archaea . BMC Microbiology . 20 . 130 . 24 May 2020 . 130 . 10.1186/s12866-020-01823-6 . 32448158 . 7247131 . free .
