| State: | RI |
| Type: | RI |
| Route: | 401 |
| Map Custom: | yes |
| Map Notes: | Route 401 highlighted in red |
| Length Mi: | 2.50 |
| Direction A: | West |
| Direction B: | East |
| Terminus A: | in East Greenwich |
| Junction: | in East Greenwich |
| Terminus B: | in East Greenwich |
| Previous Type: | I |
| Previous Route: | 295 |
| Next Type: | Route |
| Next Route: | 402 |
Route 401 is a 2.5miles state highway in East Greenwich, Rhode Island, United States.
Route 401 begins at an intersection with Route 2 (County Trail) / Division Street in East Greenwich, and begins east along a four-lane suburban road. It meets Route 4 (Col. Rodman Highway) just east at a partial cloverleaf interchange, which is exit 8 on Route 4. Route 401 continues east and crosses the Maskerchugg River, then curves southeast and crosses Dark Entry Brook. It then reaches its eastern terminus at US 1 (Main Street) / Rocky Hollow Road just west of Greenwich Cove.