| State: | RI |
| Type: | RI |
| Route: | 110 |
| Alternate Name: | Ministerial Road |
| Map Custom: | yes |
| Length Mi: | 6.1 |
| Length Round: | 1 |
| Established: | By 1969 |
| Direction A: | South |
| Direction B: | North |
| Terminus A: | in South Kingstown |
| Terminus B: | in West Kingston |
| Counties: | Washington |
| Previous Type: | Route |
| Previous Route: | 108 |
| Next Type: | Route |
| Next Route: | 112 |
Route 110 is a numbered state highway running 6.1miles wholly within the town of South Kingstown in Rhode Island. It serves to connect the University of Rhode Island to points south via U.S. Route 1 (US 1).
Route 110 begins at US 1 near the village of Perryville in South Kingstown. The route heads north for 7miles following Ministerial Road through the wetlands of the Great Swamp. Along the way it intersects with the William C. O'Neill Bike Path. Soon after crossing some railroad tracks, Route 110 ends at an intersection with Route 138 in the village of West Kingston.
Route 110 was assigned to Ministerial Road by 1969.