Zhangixalus achantharrhena is a species of frog in the family Rhacophoridae. It is endemic to Sumatra (Indonesia) and known from a number of high-elevation localities ranging from Aceh in the northwest to Lampung in the southeast. The specific name achantharrhena, from the Greek nouns (=thorn or prickle) and (=male), refers to a characteristic of males of this species: skin covered by tiny spicules.
Males grow to 411NaN1 and females (based on a single specimen) to 471NaN1 in snout–vent length. In males, the snout is sloping in lateral view and acuminate in dorsal view with a slightly spatulate tip. In the female, the snout is more rounded. The tympanum is distinct but its upper edge is hidden by the thick and conspicuous supratympanic fold. The fingers and toes are webbed and bear terminal discs. The dorsum is smooth in the female but finely spiculate in males. Dorsal coloration is bright green with reddish spots (lighter in some specimens). The dorsal surfaces of the digits, dermal appendages on the limbs and above the vent, and the lower lip are yellowish white. The venter and gular region are bright yellow. Webbing between the toes 3–5 is red but green between the other toes and the fingers.
Zhangixalus achantharrhena is known from secondary growth tropical forest where it was found in overhanging vegetation close to pools and slow-flowing streams and from close to tea plantations. Reproduction probably involves foam nests in vegetation overhanging water and aquatic tadpoles. Its elevational range is 1415m–1575mm (4,642feet–5,167feetm) above sea level. It can be locally common. However, habitat loss caused by smallholder farming and subsistence collection of wood is threatening this species. It occurs in the Kerinci Seblat National Park, but habitat loss occurs also in the park.