| Reylina G. Nicolas | |
| Office: | 13th Mayor of Santa Maria, Bulacan |
| Term Start: | June 30, 1992 |
| Term End: | June 30, 2001 |
| Predecessor: | Eriberto Ramos |
| Successor: | Bartolome Ramos |
| Office2: | Member of the Philippine House of Representatives from the Bulacan's 4th congressional district |
| Term Start2: | June 30, 2001 |
| Term End2: | June 30, 2010 |
| Predecessor2: | Angelito Sarmiento |
| Successor2: | Linabelle Villarica |
| Birth Date: | February 1, 1945 |
| Birthname: | Reylina Gustavo Nicolas |
| Birth Place: | Barangay Bagbaguin, Santa Maria, Bulacan |
| Nationality: | Filipino |
| Party: | Lakas-CMD |
| Spouse: | Ricardo D. Nicolas Jr. |
| Children: | Dimples Nicolas |
| Residence: | Bagbaguin, Santa Maria, Bulacan |
| Occupation: | Politician |
Reylina Gustavo Nicolas (born December 19, 1945) is a Filipino politician. A member of Lakas-CMD, she has been elected to three terms as the Mayor of Santa Maria, Bulacan from 1992 to 2001 and three terms as a Member of the House of Representatives of the Philippines, representing the Fourth District of Bulacan from 2001 to 2010.