Retrovirus direct repeat 1 (dr1) explained
| Retrovirus direct repeat 1 (dr1) |
| Symbol: | Retro_dr1 |
| Rfam: | RF00214 |
| Rna Type: | Cis-reg |
| Tax Domain: | Viruses |
The direct repeat 1 (dr1) element is an RNA element commonly found in the 3' UTR of Avian sarcoma, Rous sarcoma and Avian leukosis viruses (Alpharetroviruses and Avian type C retroviruses). dr1 is required for efficient viral replication and is thought to be involved in genomic RNA packaging although this may not be its only role.[1]
Notes and References
- Aschoff JM, Foster D, Coffin JM . Point mutations in the avian sarcoma/leukosis virus 3' untranslated region result in a packaging defect . Journal of Virology . 73 . 9 . 7421–7429 . September 1999 . 10.1128/JVI.73.9.7421-7429.1999 . 10438832 . 104269 .
