| Synonyms: | RAK |
| Field: | Dermatology |
| Symptoms: | Coloured freckle-like and slightly depressed flat spots arranged in a lace-like pattern |
| Onset: | Teenagers and early adulthood |
| Differential: | Dowling–Degos disease |
| Frequency: | Rare |
Reticulate acropigmentation of Kitamura is a type of pigmentation disorder of the skin.[1] It presents with coloured freckle-like and slightly depressed flat spots arranged in a lace-like pattern on the backs of hands and feet.[1] It tends to occur in skin folds of teenagers and in early adulthood, and darkens over time.[1]
It is inherited in an autosomal-dominant fashion.[1]
The condition is rare.[2] It was first described in Japan, before recognising that is also occurs elsewhere.[1]
This condition is associated with mutations in the a disintegrin and metalloproteinase domain-containing protein 10 (ADAM10) gene. This association was first shown in 2013.