| Sport: | Water polo |
| Birth Date: | 5 March 1925 |
| Birth Place: | Venice, Italy |
| Death Place: | Mestre, Italy |
Renato De Sanzuane (March 5, 1925 - June 23, 1986) was an Italian water polo player who competed in the 1952 Summer Olympics.
In 1952 he was part of the Italian team which won the bronze medal in the Olympic tournament. He played seven matches.