| Ren Wylie | |
| Position: | Center fielder |
| Birth Date: | 14 December 1861 |
| Birth Place: | Elizabeth, Pennsylvania |
| Death Place: | Wilkinsburg, Pennsylvania |
| Bats: | Right |
| Throws: | Right |
| Debutleague: | MLB |
| Debutdate: | August 11 |
| Debutyear: | 1882 |
| Debutteam: | Pittsburgh Alleghenys |
| Finalleague: | MLB |
| Finaldate: | August 11 |
| Finalyear: | 1882 |
| Finalteam: | Pittsburgh Alleghenys |
| Statleague: | MLB |
| Stat1label: | Batting average |
| Stat1value: | .000 |
| Stat2label: | Games played |
| Stat2value: | 1 |
| Stat3label: | At bats |
| Stat3value: | 3 |
| Teams: | |
James Renwick Wylie (1861–1951) was an American professional baseball player. He played one game in Major League Baseball, August 11 as a center fielder for the 1882 Pittsburgh Alleghenys. He was hitless in three at bats. He had played college baseball at Geneva College.