| René of Alençon | |
| Duke of Alençon Count of Perche | |
| Noble Family: | House of Valois-Alençon |
| Father: | John II of Alençon |
| Mother: | Marie of Armagnac |
| Spouse: | Marguerite of Harcourt Margaret of Lorraine |
| Birth Date: | 1454 |
| Death Place: | Chateau d'Alençon |
René of Alençon (1454 – 1 November 1492) was a French nobleman. He succeeded his father John II of Alençon as Duke of Alençon.
René was born in 1454 to the House of Valois-Alençon. He was the son of John II of Alençon and Marie of Armagnac.
In 1478, he was restored as Duke of Alençon and Count of Perche, titles which had been confiscated from his family after his father's conviction in 1474.
His first wife was Marguerite, daughter of William of Harcourt, Count of Tancarville.
He married a second time on 14 May 1488 at Toul, to Margaret of Lorraine (1463 - 1 November 1521), daughter of Frederick, Count of Vaudémont and Yolande of Anjou. Margaret bore him three children:
He also had several illegitimate children: