| René Vandenberghe | |
| Birth Date: | 5 March 1887 |
| Birth Place: | Pittem, Belgium |
| Death Place: | Roeselare, Belgium |
| Discipline: | Road |
| Role: | Rider |
| Proyears1: | 1909 |
| Proyears2: | 1910 |
| Proteam2: | Individual |
| Proyears3: | 1911 |
| Proyears4: | 1912–1913 |
| Proteam4: | Thomann |
| Proyears5: | 1913 |
| Proyears6: | 1914 |
| Proteam6: | JB Louvet–Continental |
| Proyears7: | 1914 |
| Proteam7: | Liberator |
| Proyears8: | 1921 |
| Proteam8: | Individual |
René Vandenberghe (5 March 1887 – 3 July 1958) was a Belgian road cyclist. Professional from 1909 to 1921, he won the Tour of Belgium in 1911. He also rode in the Tour de France four times, with his best result being 12th in 1912. That year, he also finished 2nd in two stages and 3rd in two stages of the race.[1]