| Regnière-Écluse | |
| Commune Status: | Commune |
| Arrondissement: | Abbeville |
| Canton: | Rue |
| Intercommunality: | CC Ponthieu-Marquenterre |
| Insee: | 80665 |
| Postal Code: | 80120 |
| Mayor: | Patrick Bost[1] |
| Term: | 2020 - 2026 |
| Coordinates: | 50.2817°N 1.7681°W |
| Elevation M: | 17 |
| Elevation Min M: | 5 |
| Elevation Max M: | 60 |
| Area Km2: | 9.54 |
Regnière-Écluse is a commune in the Somme department in Hauts-de-France in northern France.
The commune is situated some 14miles north of Abbeville, on the D938 road and surrounded by the forest of Crécy-en-Ponthieu.