Puebla is one of the smallest states of Mexico. With nearly 34e3km2, it is 21st in area within all federal units (Spanish: entidades federativas). Despite that, it is the sixth most populous state, with approximately 6 million persons. Puebla is also the second state with higher number of municipalities, only behind the state of Oaxaca. The municipalities of Puebla are grouped into seven regions.
| Municipalities of Región I - Huauchinango | |||
| INGEI Code | Municipality | Municipal Seat | Population |
| 006 | Ahuacatlán | Ahuacatlán | 13.058 |
| 008 | Ahuazotepec | Ahuazotepec | 9.087 |
| 014 | Amixtlán | Amixtlán | 4.704 |
| 016 | Aquixtla | Aquixtla | 7.664 |
| 028 | Camocuautla | Camocuautla | 2.160 |
| 030 | Coatepec | Coatepec | 884 |
| 039 | Cuautempan | San Esteban Cuautempan | 8.984 |
| 049 | Chiconcuautla | Chiconcuautla | 12.855 |
| 053 | Chignahuapan | Chignahuapan | 49.266 |
| 057 | Honey | Chila Honey | 7.279 |
| 064 | Francisco Z. Mena | Metlaltoyuca | 16.331 |
| 068 | Hermenegildo Galeana | Bienvenido | 8.194 |
| 071 | Huauchinango | Huauchinango | 83.537 |
| 083 | Ixtacamaxtitlán | Ixtacamaxtitlán | 28.358 |
| 086 | Jalpan | Jalpan | 13.257 |
| 091 | Juan Galindo | Nuevo Necaxa | 9.301 |
| 100 | Naupan | Naupan | 9.613 |
| 109 | Pahuatlán | Pahuatlán de Valle | 18.326 |
| 111 | Pantepec | Pantepec | 19.401 |
| 123 | San Felipe Tepatlán | San Felipe Tepatlán | 4.425 |
| 162 | Tepango de Rodríguez | Tepango de Rodríguez | 4.003 |
| 167 | Tepetzintla | Tepetzintla | 9.457 |
| 172 | Tetela de Ocampo | Tetela de Ocampo | 25.859 |
| 178 | Tlacuilotepec | Tlacuilotepec | 17.764 |
| 183 | Tlaola | Tlaola | 18.233 |
| 184 | Tlapacoya | Tlapacoya | 6.502 |
| 187 | Tlaxco | Tlaxco | 6.271 |
| 194 | Venustiano Carranza | Venustiano Carranza | 25.115 |
| 197 | Xicotepec de Juárez | Xicotepec de Juárez | 70.164 |
| 208 | Zacatlán | Zacatlán | 69.698 |
| 213 | Zihuateutla | Zihuateutla | 13.535 |
| Municipalities of Región II - Teziutlán | |||
| INGEI Code | Municipality | Municipal Seat | Population |
| 002 | Acateno | San José Acateno | 9.199 |
| 017 | Atempan | Atempan | 18.565 |
| 025 | Ayotoxco de Guerrero | Ayotoxco de Guerrero | 7.704 |
| 029 | Caxhuacan | Caxhuacan | 3.931 |
| 043 | Cuetzalan del Progreso | Ciudad de Cuetzalan | 45.010 |
| 054 | Chignautla | Chignautla | 21.571 |
| 072 | Huehuetla | Huehuetla | 16.130 |
| 075 | Hueyapan | Hueyapan | 10.206 |
| 076 | Hueytamalco | Hueytamalco | 28.345 |
| 078 | Huitzilan de Serdán | Huitzilan | 11.670 |
| 080 | Atlequizayan | Atlequizayan | 2.761 |
| 084 | Ixtepec | Ixtepec | 6.589 |
| 088 | Jonotla | Jonotla | 4.942 |
| 101 | Nauzontla | Nauzontla | 3.617 |
| 107 | Olintla | Olintla | 12.609 |
| 158 | Tenampulco | Tenampulco | 7.060 |
| 173 | Teteles de Ávila Castillo | Teteles de Ávila Castillo | 5.556 |
| 174 | Teziutlán | Teziutlán | 81.156 |
| 186 | Tlatlauquitepec | Ciudad de Tlatlauquitepec | 47.106 |
| 192 | Tuzamapan de Galeana | Tuzamapan de Galeana | 6.176 |
| 199 | Xiutetelco | San Juan Xiutetelco | 30.426 |
| 200 | Xochiapulco | Cinco de Mayo | 4.306 |
| 202 | Xochitlán de Vicente Suárez | Xochitlán de Romero Rubio | 11.760 |
| 204 | Yaonáhuac | Yaonáhuac | 6.649 |
| 207 | Zacapoaxtla | Zacapoaxtla | 49.242 |
| 210 | Zapotitlán de Méndez | Zapotitlán de Méndez | 5.267 |
| 211 | Zaragoza | Zaragoza | 13.810 |
| 212 | Zautla | Santiago Zautla | 19.447 |
| 215 | Zongozotla | Zongozotla | 4.392 |
| 216 | Zoquiapan | Zoquiapan | 2.949 |
| Municipalities of Región III - Ciudad Serdán | |||
| INGEI Code | Municipality | Municipal Seat | Population |
| 012 | Aljojuca | Aljojuca | 6.632 |
| 023 | Atzitzintla | Atzitzintla | 8.104 |
| 044 | Cuyoaco | Cuyoaco | 14.434 |
| 045 | Chalchicomula de Sesma | Ciudad Serdán | 38.711 |
| 050 | Chichiquila | Chichiquila | 20.252 |
| 058 | Chilchotla | Rafael J. García | 17.833 |
| 063 | Esperanza | Esperanza | 13.473 |
| 067 | Guadalupe Victoria | Guadalupe Victoria | 14.833 |
| 093 | Lafragua | Saltillo | 9.207 |
| 094 | Libres | Ciudad de Libres | 25.719 |
| 096 | Mazapiltepec de Juárez | Mazapiltepec de Juárez | 2.396 |
| 099 | Cañada Morelos | Morelos Cañada | 17.779 |
| 104 | Nopalucan | Nopalucan de la Granja | 19.033 |
| 105 | Ocotepec | Ocotepec | 4.945 |
| 108 | Oriental | Oriental | 13.769 |