| Reginald Ruffin | |
| Current Title: | Athletic director |
| Current Team: | Tuskegee |
| Current Conference: | SIAC |
| Player Years1: | 1994–1997 |
| Player Team1: | North Alabama |
| Player Positions: | Defensive end, linebacker |
| Coach Years1: | 2002–2003 |
| Coach Team1: | Tuskegee (assistant) |
| Coach Years2: | 2006–2010 |
| Coach Team2: | Tuskegee (DC/LB) |
| Coach Years3: | 2011–2021 |
| Coach Team3: | Miles |
| Coach Years4: | 2022 |
| Coach Team4: | Tuskegee |
| Admin Years1: | 2021–present |
| Admin Team1: | Tuskegee |
| Overall Record: | 73–47 |
| Bowl Record: | 0–1 |
| Tournament Record: | 0–2 (NCAA D-II playoffs) |
| Championships: | 4 SIAC (2011, 2015, 2018–2019) 7 SIAC West Division (2011, 2013, 2015, 2018–2019, 2021–2022) |
Reginald Ruffin is an American college football coach and athletics administrator. He is athletic director at Tuskegee University in Tuskegee, Alabama, a position he has held since December 2021.[1] Ruffin served as the head football coach at Miles College in Fairfield, Alabama from 2011 to 2021.[2]