Rapp–Hodgkin syndrome explained

Rapp–Hodgkin syndrome was formerly thought to be a unique autosomal dominant disorder due to a P63 gene mutation. However, it was recently shown to the same disease as Hay–Wells syndrome.^[1]

It was first characterized in 1968.^[2]

See also

• Punctate porokeratosis
• List of cutaneous conditions

Further reading

• GeneReviews/NCBI/NIH/UW entry on Ankyloblepharon-Ectodermal Defects-Cleft Lip/Palate Syndrome or AEC Syndrome, Hay–Wells Syndrome. Includes: Rapp–Hodgkin Syndrome

External links

• OMIM entries on AEC

Notes and References

1. Clements SE, Techanukul T, Holden ST, etal . Rapp–Hodgkin and Hay–Wells ectodermal dysplasia syndromes represent a variable spectrum of the same genetic disorder . Br. J. Dermatol. . 163 . 3 . 624–9 . September 2010 . 20491771 . 10.1111/j.1365-2133.2010.09859.x . 44866051 .
2. Rapp RS, Hodgkin WE . Anhidrotic ectodermal dysplasia: autosomal dominant inheritance with palate and lip anomalies . J. Med. Genet. . 5 . 4 . 269–72 . December 1968 . 5713637 . 1468665 . 10.1136/jmg.5.4.269.