Rachel E. Klevit Explained

Rachel E. Klevit
Alma Mater:	Reed College, BA, 1978 Oxford University, D.Phil, 1981

Rachel E. Klevit is professor of biochemistry, adjunct professor of chemistry, and adjunct professor of pharmacology at the University of Washington. She holds the Edmond H. Fischer-Washington Research Foundation Endowed Chair in Biochemistry. Klevit's research focuses on molecular interactions in human diseases and includes research on BRCA1, the protein ubiquitination system, and human heat shock proteins.^{[1] [2] [3]}

Education

Klevit received her B.A. in 1978 from Reed College and her D.Phil. from Oxford University in 1981. She completed her post-doctoral training at Duke University Medical Center.

Awards

Klevit was awarded a Rhodes Scholarship in 1978 to attend Oxford University.^[4] She received the Margaret Oakley Dayhoff Award in Biophysics from the Biophysical Society in 1987–1988, the Fritz Lippmann Award from the American Society for Biochemistry and Molecular Biology in 2015, and the Dorothy Crowfoot Hodgkin Award from the Protein Society in 2016.^[5]

In 2021, she was elected member of the U. S. National Academy of Sciences.^[6]

External links

• Faculty web page
• Department of Pharmacology web page
• Description of work on BRCA1 structure

Notes and References

1. Christensen. DE. Brzovic. PS. Klevit. RE. E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages.. Nature Structural & Molecular Biology. October 2007. 14. 10. 941–8. 17873885. 10.1038/nsmb1295.
2. Vittal. V. Wenzel. DM. Brzovic. PS. Klevit. RE. Biochemical and structural characterization of the ubiquitin-conjugating enzyme UBE2W reveals the formation of a noncovalent homodimer.. Cell Biochemistry and Biophysics. September 2013. 67. 1. 103–10. 23709311. 10.1007/s12013-013-9633-5. 3758794.
3. Delbecq. SP. Rosenbaum. JC. Klevit. RE. A Mechanism of Subunit Recruitment in Human Small Heat Shock Protein Oligomers.. Biochemistry. 21 July 2015. 54. 28. 4276–84. 26098708. 10.1021/acs.biochem.5b00490. 4512712.
4. Web site: Biochemist Joins National Academy of Sciences . 2022-03-16 . Reed Magazine . en-us.
5. . 2016-03-08 . The Protein Society Announces Its 2016 Award Recipients . dead. Baltimore, MD. The Protein Society. https://web.archive.org/web/20160830222907/http://www.proteinsociety.org/protein-society-awards/2016-award-winners-press-release/. 2016-08-30. 2017-03-10.
6. Web site: News from the National Academy of Sciences. April 26, 2021. July 4, 2021. Newly elected members and their affiliations at the time of election are: … Klevit, Rachel; professor, department of biochemistry, University of Washington, Seattle., entry in member directory:Web site: Member Directory. July 4, 2021. National Academy of Sciences.