Rachel Dutton Explained

Honorific Prefix:Professor
Rachel Dutton
Honorific Suffix:Ph.D.
Nationality:American
Workplaces:Harvard University
University of California, San Diego
Thesis Title:Vitamin K epoxide reductase homologues provide an alternative pathway for bacterial disulfide bond formation
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Thesis Year:2010
Doctoral Advisor:Jon Beckwith
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Website:Lab Website

Rachel Dutton is an American microbiologist. She has developed the microorganisms that live on cheese into a model system for complex interacting microbial communities. She has worked with chefs including Dan Felder, head of research and development at Momofuku to develop new fermentation procedures to be used in food[1] [2] and has been called the "go-to microbiologist" for chefs and gastronomists.

She is an assistant professor in the Division of Biological Sciences at the University of California, San Diego.

Early life and education

Dutton grew up in South San Francisco, California. She earned her B.Sc. in molecular biology at the University of California, San Diego in 2002. She performed her Ph.D. work in the laboratory of Jon Beckwith at Harvard Medical School, graduating in 2010.

Career

In 2010, Dutton became an independent Bauer Fellow at Harvard University, where she initiated a study of the microbial communities that live on cheese and give cheeses their particular flavors.[3] She reasoned that cheese microbes would be less complex and more consistent than other microbial communities such as the gut microbiome or soil microorganisms,[4] and therefore act as a model system in which principles of microbial interactions in more complex communities and ecosystems could be investigated.[5] To begin her studies, she learned to make cheese herself, and collaborated with local artisan cheesemakers.[6] [7] By sequencing the microorganisms found on 137 cheese rinds from 10 different countries, she identified 24 genera of bacteria and fungi that are dominant in cheese microbial communities.[8] She developed a microbiological culture system that mimics the normal conditions of community formation to reconstruct and manipulate the interactions between species in these communities, identifying widespread bacterial-fungal interactions.[9] [10] She uses these cultures to investigate the genetic requirements for community interactions[11] [12] and how horizontal gene transfer affects the genetic makeup of species in these communities.[13]

Dutton collaborates widely with chefs and cheesemakers, and has appeared in the Netflix documentary Cooked, (episode 4[14]) the PBS documentary series The Mind of a Chef,[15] (season 1, episode 2[16]), and on the podcasts Science Friday[17] and Meet the Microbiologist.[18]

In 2015 Dutton moved to the University of California, San Diego, where she is an assistant professor in the Division of Biological Sciences, Section on Molecular Biology.[19] [3]

Awards

External links

Notes and References

  1. Momofuku Puts Mold, Bacteria on the Menu. Smith. Peter Andrey. 2012-05-16. Wired. 2019-03-10. 1059-1028.
  2. Web site: Fish Sauce, Ketchup and the Rewilding of Our Food. Smith. Peter. Smithsonian. en. 2019-03-10.
  3. Web site: Molecular biologist talks cheese. phys.org. en-us. 2019-03-10.
  4. Button. Julie E.. Dutton. Rachel J.. 2012-08-07. Cheese microbes. Current Biology. 22. 15. R587–589. 10.1016/j.cub.2012.06.014. 1879-0445. 22877773. free.
  5. Wolfe. Benjamin E.. Dutton. Rachel J.. 2013. Towards an Ecosystem Approach to Cheese Microbiology. Microbiology Spectrum. 1. 1. 10.1128/microbiolspec.CM-0012-12. 2165-0497. 26184819.
  6. News: For Gastronomists, a Go-To Microbiologist. Smith. Peter Andrey. 2012-09-17. The New York Times. 2019-03-10. en-US. 0362-4331.
  7. News: Small Cheese Makers Invest in a Stinky Science. Zimberoff. Larissa. 2017-02-06. The New York Times. 2019-03-10. en-US. 0362-4331.
  8. Wolfe. Benjamin E.. Button. Julie E.. Santarelli. Marcela. Dutton. Rachel J.. 2014-07-17. Cheese rind communities provide tractable systems for in situ and in vitro studies of microbial diversity. Cell. 158. 2. 422–433. 10.1016/j.cell.2014.05.041. 1097-4172. 4222527. 25036636.
  9. Scientists Uncover a Surprising World of Microbes in Cheese Rind. Miller. Greg. 2014-07-31. Wired. 2019-03-10. 1059-1028.
  10. Web site: Cheese-based research. 2014-07-28. Harvard Gazette. en-US. 2019-03-10.
  11. Morin. Manon. Pierce. Emily C.. Dutton. Rachel J.. 2018. Changes in the genetic requirements for microbial interactions with increasing community complexity. eLife. 7. 10.7554/eLife.37072. 2050-084X. 6175579. 30211673 . free .
  12. Web site: Competition and Cooperation of Cheese Rind Microbes Exposed. The Scientist Magazine®. en. 2019-03-10.
  13. Bonham. Kevin S.. Wolfe. Benjamin E.. Dutton. Rachel J.. 2017. Extensive horizontal gene transfer in cheese-associated bacteria. eLife. 6. 10.7554/eLife.22144. 2050-084X. 5526665. 28644126 . free .
  14. Web site: Cooked (2015) s01e04 Episode Script SS. Springfield! Springfield!. 2019-03-10.
  15. Web site: Rachel Dutton. 2013-08-20. Science & Food. 2019-10-08.
  16. Web site: Welcome to the Dutton Lab. The Dutton Lab @ UCSD. en-US. 2019-10-08.
  17. Web site: A Wedge of Science: A Spotlight on Cheese. Science Friday. en-US. 2019-03-10.
  18. Web site: The Cheese Microbiome with Rachel Dutton. ASM.org. en. 2019-10-08.
  19. Web site: Say Cheese. Buschman. Heather. McDonald. Kim. 2016-11-01. Triton. en-US. 2019-03-10. Ph.D. ’08.
  20. Web site: FAS Center: Rachel Dutton. archive.sysbio.harvard.edu. 2019-10-08.
  21. Web site: Dutton, Rachel. The David and Lucile Packard Foundation. en-US. 2019-03-10.
  22. Web site: UC San Diego Biologists Named Pew Scholars. ucsdnews.ucsd.edu. 2019-03-10.
  23. Web site: New Innovator Award Recipients. commonfund.nih.gov. 26 June 2013. 2019-03-10.