RTI-352 explained

RTI-352 is a phenyltropane that is used as a radiolabeling ligand for the DAT.

RTI-352 is a geometric isomer of RTI-55 (β-CIT).[1]

Based on X-ray crystallography, this compound is in a tautomeric equilibrium residing mostly on the side of the boat-shaped conformer.

Notes and References

  1. 10.1002/(SICI)1098-2396(199704)25:4<389::AID-SYN10>3.0.CO;2-Q . RTI-352: A 3α Analogue of RTI-55 as an in vivo dopamine transporter binding ligand . Synapse . 25 . 4 . 389–392 . 1997 . Zhan . Yougen . Saindane . Amit M. . Scheffel . Ursula . Carroll . F. Ivy . Holmquist . Christopher R. . Kepler . John A. . Taylor . George F. . Kuhar . Michael J. . 9097398 .

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