RTI-160 explained

RTI-160 (benzoylecgonine dimethylamide) is a tropane derivative drug with stimulant effects, having similar potency as a dopamine reuptake inhibitor to cocaine. It is synthesized by an amide condensation reaction between benzoylecgonine and dimethylamine.^{[1] [2]}

See also

• 3-(p-Fluorobenzoyloxy)tropane
• 4′-Fluorococaine
• Cocaethylene
• Cocaine reverse ester
• RTI-229
• Salicylmethylecgonine

Notes and References

1. Carroll FI, Kotian P, Dehghani A, Gray JL, Kuzemko MA, Parham KA, Abraham P, Lewin AH, Boja JW, Kuhar MJ . 6 . Cocaine and 3 beta-(4'-substituted phenyl)tropane-2 beta-carboxylic acid ester and amide analogues. New high-affinity and selective compounds for the dopamine transporter . Journal of Medicinal Chemistry . 38 . 2 . 379–388 . January 1995 . 10.1021/jm00002a020 . 7830281 .
2. Paula S, Tabet MR, Farr CD, Norman AB, Ball WJ . Three-dimensional quantitative structure-activity relationship modeling of cocaine binding by a novel human monoclonal antibody . Journal of Medicinal Chemistry . 47 . 1 . 133–142 . January 2004 . 10.1021/jm030351z . 14695827 .