RNF24 explained

Ring finger protein 24 is a protein that in humans is encoded by the RNF24 gene.^{[1] [2]}

RNF24 binds TRPC6 (603652) and other transient receptor potential cation channel (TRPC) family members and is involved in regulation of intracellular trafficking of TRPCs.^[2] In addition, RNF24 contains similarity to the Drosophila goliath protein and thus may function as a transcription factor.^[1]

Further reading

• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2002 . 12477932 . 10.1073/pnas.242603899 . 139241. 2002PNAS...9916899M . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928.
• Zhang QH, Ye M, Wu XY, etal . Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. . Genome Res. . 10 . 10 . 1546–60 . 2000 . 11042152 . 10.1101/gr.140200 . 310934.
• Deloukas P, Matthews LH, Ashurst J, etal . The DNA sequence and comparative analysis of human chromosome 20. . Nature . 414 . 6866 . 865–71 . 2001. 11780052 . 10.1038/414865a . 2001Natur.414..865D . free .

Notes and References

1. Web site: Entrez Gene: ring finger protein 24.
2. Lussier MP, Lepage PK, Bousquet SM, Boulay G . RNF24, a new TRPC interacting protein, causes the intracellular retention of TRPC . Cell Calcium . 43 . 5 . 432–43 . May 2008 . 17850865 . 10.1016/j.ceca.2007.07.009 .