RNA Modification Base explained

RMBase
Description:	decoding the landscape of RNA modifications identified from high-throughput sequencing datasets.
Center:	Sun Yat-sen University
Laboratory:	Key Laboratory of Gene Engineering of the Ministry of Education
Author:	Jian-Hua Yang
Citation:	Sun & al. (2015)^[1]
Released:	2010
Url:	http://rna.sysu.edu.cn/rmbase/

RNA Modification Base (RMBase)^{[2] [3]} is designed for decoding the landscape of RNA modifications identified from high-throughput sequencing data (MeRIP-seq, m6A-seq, miCLIP, m6A-CLIP, Pseudo-seq, Ψ-seq, CeU-seq, Aza-IP, RiboMeth-seq). It contains ~124200 N6-Methyladenosines (m6A), ~9500 pseudouridine (Ψ) modifications, ~1000 5-methylcytosine (m5C) modifications, ~1210 2′-O-methylations (2′-O-Me) and ~3130 other types of RNA modifications. RMBase demonstrated thousands of RNA modifications located within mRNAs, regulatory ncRNAs (e.g. lncRNAs, miRNAs, pseudogenes, circRNAs, snoRNAs, tRNAs), miRNA target sites and disease-related SNPs.

See also

• RNA modification database
• RNA modification

External links

• http://rna.sysu.edu.cn/rmbase/

Notes and References

1. Sun. WJ. Li. JH. Liu. S. Wu. J. Zhou. H. Qu. LH. Yang. JH. RMBase: a resource for decoding the landscape of RNA modifications from high-throughput sequencing data.. Nucleic Acids Research. 11 October 2015. 26464443. 10.1093/nar/gkv1036. D259–D265. 4702777. 44. D1 .
2. Sun. WJ. Li. JH. Liu. S. Wu. J. Zhou. H. Qu. LH. Yang. JH. RMBase: a resource for decoding the landscape of RNA modifications from high-throughput sequencing data.. Nucleic Acids Research. 11 October 2015. 26464443. 10.1093/nar/gkv1036. D259–D265. 4702777. 44. D1 .
3. Xuan. JJ. Sun. WJ. Lin. PH. Zhou. KR. Liu. S. Zheng. LL. Qu. LH. Yang. JH. RMBase v2.0: deciphering the map of RNA modifications from epitranscriptome sequencing data.. Nucleic Acids Research. 4 January 2018. 46. D1. D327–D334. 10.1093/nar/gkx934. 29040692. 5753293.