RINT1 explained

RAD50-interacting protein 1 is a protein that in humans is encoded by the RINT1 gene.^{[1] [2] [3]}

Interactions

RINT1 has been shown to interact with Rad50 and ZW10.

Further reading

• Toward a complete human genome sequence . Genome Res. . 8 . 11 . 1097–108 . 1999 . 9847074 . 10.1101/gr.8.11.1097. free . Sanger Centre . The . Washington University Genome Sequencing Cente . The .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Hillier LW, Fulton RS, Fulton LA, etal . The DNA sequence of human chromosome 7 . Nature . 424 . 6945 . 157–64 . 2003 . 12853948 . 10.1038/nature01782 . 2003Natur.424..157H . free .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Nakajima K, Hirose H, Taniguchi M, etal . Involvement of BNIP1 in apoptosis and endoplasmic reticulum membrane fusion . EMBO J. . 23 . 16 . 3216–26 . 2005 . 15272311 . 10.1038/sj.emboj.7600333 . 514507 .
• Gerhard DS, Wagner L, Feingold EA, etal . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Arasaki K, Taniguchi M, Tani K, Tagaya M . RINT-1 Regulates the Localization and Entry of ZW10 to the Syntaxin 18 Complex . Mol. Biol. Cell . 17 . 6 . 2780–8 . 2006 . 16571679 . 10.1091/mbc.E05-10-0973 . 1474792 .
• Kong LJ, Meloni AR, Nevins JR . The Rb-related p130 protein controls telomere lengthening through an interaction with a Rad50-interacting protein, RINT-1 . Mol. Cell . 22 . 1 . 63–71 . 2006 . 16600870 . 10.1016/j.molcel.2006.02.016 . free .
• Lin X, Liu CC, Gao Q, etal . RINT-1 Serves as a Tumor Suppressor and Maintains Golgi Dynamics and Centrosome Integrity for Cell Survival . Mol. Cell. Biol. . 27 . 13 . 4905–16 . 2007 . 17470549 . 10.1128/MCB.02396-06 . 1951495 .
• Sun Y, Shestakova A, Hunt L, etal . Rab6 Regulates Both ZW10/RINT-1– and Conserved Oligomeric Golgi Complex-dependent Golgi Trafficking and Homeostasis . Mol. Biol. Cell . 18 . 10 . 4129–42 . 2007 . 17699596 . 10.1091/mbc.E07-01-0080 . 1995728 .

Notes and References

1. Xiao J, Liu CC, Chen PL, Lee WH . RINT-1, a novel Rad50-interacting protein, participates in radiation-induced G(2)/M checkpoint control . J Biol Chem . 276 . 9 . 6105–11 . Mar 2001 . 11096100 . 10.1074/jbc.M008893200 . free .
2. Hirose H, Arasaki K, Dohmae N, Takio K, Hatsuzawa K, Nagahama M, Tani K, Yamamoto A, Tohyama M, Tagaya M . Implication of ZW10 in membrane trafficking between the endoplasmic reticulum and Golgi . EMBO J . 23 . 6 . 1267–78 . Mar 2004 . 15029241 . 381410 . 10.1038/sj.emboj.7600135 .
3. Web site: Entrez Gene: RINT1 RAD50 interactor 1.