RBM15 explained
Putative RNA-binding protein 15 is a protein that in humans is encoded by the RBM15 gene.[1] [2] [3] It is an RNA-binding protein that acts as a key regulator of N6-Methyladenosine (m6A) methylation of RNAs[4]
Further reading
- Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
- Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
- Beausoleil SA, Jedrychowski M, Schwartz D, etal . Large-scale characterization of HeLa cell nuclear phosphoproteins. . Proc. Natl. Acad. Sci. U.S.A. . 101 . 33 . 12130–5 . 2004 . 15302935 . 10.1073/pnas.0404720101 . 514446 . 2004PNAS..10112130B . free .
- Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
- Hsiao HH, Yang MY, Liu YC, etal . RBM15-MKL1 (OTT-MAL) fusion transcript in an adult acute myeloid leukemia patient. . Am. J. Hematol. . 79 . 1 . 43–5 . 2005 . 15849773 . 10.1002/ajh.20298 . 30859557 . free .
- Gregory SG, Barlow KF, McLay KE, etal . The DNA sequence and biological annotation of human chromosome 1. . Nature . 441 . 7091 . 315–21 . 2006 . 16710414 . 10.1038/nature04727 . 2006Natur.441..315G . free .
- Beausoleil SA, Villén J, Gerber SA, etal . A probability-based approach for high-throughput protein phosphorylation analysis and site localization. . Nat. Biotechnol. . 24 . 10 . 1285–92 . 2006 . 16964243 . 10.1038/nbt1240 . 14294292 .
- Lindtner S, Zolotukhin AS, Uranishi H, etal . RNA-binding motif protein 15 binds to the RNA transport element RTE and provides a direct link to the NXF1 export pathway. . J. Biol. Chem. . 281 . 48 . 36915–28 . 2007 . 17001072 . 10.1074/jbc.M608745200 . free .
- Olsen JV, Blagoev B, Gnad F, etal . Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. . Cell . 127 . 3 . 635–48 . 2006 . 17081983 . 10.1016/j.cell.2006.09.026 . 7827573 . free .
Notes and References
- Ma Z, Morris SW, Valentine V, Li M, Herbrick JA, Cui X, Bouman D, Li Y, Mehta PK, Nizetic D, Kaneko Y, Chan GC, Chan LC, Squire J, Scherer SW, Hitzler JK . Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia . Nat Genet . 28 . 3 . 220–1 . Jun 2001 . 11431691 . 10.1038/90054 . 36236342 .
- Mercher T, Coniat MB, Monni R, Mauchauffe M, Nguyen Khac F, Gressin L, Mugneret F, Leblanc T, Dastugue N, Berger R, Bernard OA . Involvement of a human gene related to the Drosophila spen gene in the recurrent t(1;22) translocation of acute megakaryocytic leukemia . Proc Natl Acad Sci U S A . 98 . 10 . 5776–9 . May 2001 . 11344311 . 33289 . 10.1073/pnas.101001498 . 2001PNAS...98.5776M . free .
- Web site: Entrez Gene: RBM15 RNA binding motif protein 15.
- Web site: UniProtKB - Q96T37 (RBM15_HUMAN) . 29 October 2018.
