RASGEF1A explained

RasGEF domain family, member 1A is a protein that in humans is encoded by the RASGEF1A gene.^[1]

Further reading

• Ura K, Obama K, Satoh S, Sakai Y, Nakamura Y, Furukawa Y . Enhanced RASGEF1A expression is involved in the growth and migration of intrahepatic cholangiocarcinoma . Clinical Cancer Research . 12 . 22 . 6611–6 . Nov 2006 . 17121879 . 10.1158/1078-0432.CCR-06-0783 . free .
• Emison ES, McCallion AS, Kashuk CS, Bush RT, Grice E, Lin S, Portnoy ME, Cutler DJ, Green ED, Chakravarti A . A common sex-dependent mutation in a RET enhancer underlies Hirschsprung disease risk . Nature . 434 . 7035 . 857–63 . Apr 2005 . 15829955 . 10.1038/nature03467 . 2005Natur.434..857E . 4312809 .
• Garcia-Barcelo MM, Tang CS, Ngan ES, Lui VC, Chen Y, So MT, Leon TY, Miao XP, Shum CK, Liu FQ, Yeung MY, Yuan ZW, Guo WH, Liu L, Sun XB, Huang LM, Tou JF, Song YQ, Chan D, Cheung KM, Wong KK, Cherny SS, Sham PC, Tam PK . Genome-wide association study identifies NRG1 as a susceptibility locus for Hirschsprung's disease . Proceedings of the National Academy of Sciences of the United States of America . 106 . 8 . 2694–9 . Feb 2009 . 19196962 . 10.1073/pnas.0809630105 . 2650328. free . 2009PNAS..106.2694G .
• Yaman E, Gasper R, Koerner C, Wittinghofer A, Tazebay UH . RasGEF1A and RasGEF1B are guanine nucleotide exchange factors that discriminate between Rap GTP-binding proteins and mediate Rap2-specific nucleotide exchange . The FEBS Journal . 276 . 16 . 4607–16 . Aug 2009 . 19645719 . 10.1111/j.1742-4658.2009.07166.x . 11693/22668 . 13584642 . free .
• Burzynski GM, Nolte IM, Bronda A, Bos KK, Osinga J, Plaza Menacho I, Twigt B, Maas S, Brooks AS, Verheij JB, Buys CH, Hofstra RM . Identifying candidate Hirschsprung disease-associated RET variants . American Journal of Human Genetics . 76 . 5 . 850–8 . May 2005 . 15759212 . 10.1086/429589 . 1199373.

Notes and References

1. Web site: Entrez Gene: RasGEF domain family, member 1A .