RAB5B explained

Ras-related protein Rab-5B is a protein that in humans is encoded by the RAB5B gene.^{[1] [2] [3]}

Further reading

• Bucci C, Lütcke A, Steele-Mortimer O, Olkkonen VM, Dupree P, Chiariello M, Bruni CB, Simons K, Zerial M . Co-operative regulation of endocytosis by three Rab5 isoforms. . FEBS Lett. . 366 . 1 . 65–71 . 1995 . 7789520 . 10.1016/0014-5793(95)00477-Q . 40284549 . free .
• Korenberg JR, Chen XN, Adams MD, Venter JC . Toward a cDNA map of the human genome. . Genomics . 29 . 2 . 364–70 . 1996 . 8666383 . 10.1006/geno.1995.9993 .
• Bao S, Zhu J, Garvey WT . Cloning of Rab GTPases expressed in human skeletal muscle: studies in insulin-resistant subjects. . Horm. Metab. Res. . 30 . 11 . 656–62 . 1999 . 9918381 . 10.1055/s-2007-978953 . 23540699 .
• Callaghan J, Nixon S, Bucci C, Toh BH, Stenmark H . Direct interaction of EEA1 with Rab5b. . Eur. J. Biochem. . 265 . 1 . 361–6 . 1999 . 10491193 . 10.1046/j.1432-1327.1999.00743.x . free .
• Hartley JL, Temple GF, Brasch MA . DNA cloning using in vitro site-specific recombination. . Genome Res. . 10 . 11 . 1788–95 . 2001 . 11076863 . 310948 . 10.1101/gr.143000 .
• Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A . Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. . Genome Res. . 11 . 3 . 422–35 . 2001 . 11230166 . 311072 . 10.1101/gr.GR1547R .
• Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S . Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. . EMBO Rep. . 1 . 3 . 287–92 . 2001 . 11256614 . 1083732 . 10.1093/embo-reports/kvd058 .
• Tall GG, Barbieri MA, Stahl PD, Horazdovsky BF . Ras-activated endocytosis is mediated by the Rab5 guanine nucleotide exchange activity of RIN1. . Dev. Cell . 1 . 1 . 73–82 . 2001 . 11703925 . 10.1016/S1534-5807(01)00008-9 . free .
• Saito K, Murai J, Kajiho H, Kontani K, Kurosu H, Katada T . A novel binding protein composed of homophilic tetramer exhibits unique properties for the small GTPase Rab5. . J. Biol. Chem. . 277 . 5 . 3412–8 . 2002 . 11733506 . 10.1074/jbc.M106276200 . free .
• Merithew E, Stone C, Eathiraj S, Lambright DG . Determinants of Rab5 interaction with the N terminus of early endosome antigen 1. . J. Biol. Chem. . 278 . 10 . 8494–500 . 2003 . 12493736 . 10.1074/jbc.M211514200 . free .
• Kajiho H, Saito K, Tsujita K, Kontani K, Araki Y, Kurosu H, Katada T . RIN3: a novel Rab5 GEF interacting with amphiphysin II involved in the early endocytic pathway. . J. Cell Sci. . 116 . Pt 20 . 4159–68 . 2004 . 12972505 . 10.1242/jcs.00718 . free .
• Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A . From ORFeome to biology: a functional genomics pipeline. . Genome Res. . 14 . 10B . 2136–44 . 2004 . 15489336 . 528930 . 10.1101/gr.2576704 .
• Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S . The LIFEdb database in 2006. . Nucleic Acids Res. . 34 . Database issue . D415–8 . 2006 . 16381901 . 1347501 . 10.1093/nar/gkj139 .
• Chi A, Valencia JC, Hu ZZ, Watabe H, Yamaguchi H, Mangini NJ, Huang H, Canfield VA, Cheng KC, Yang F, Abe R, Yamagishi S, Shabanowitz J, Hearing VJ, Wu C, Appella E, Hunt DF . Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes. . J. Proteome Res. . 5 . 11 . 3135–44 . 2007 . 17081065 . 10.1021/pr060363j .
• Hirota Y, Kuronita T, Fujita H, Tanaka Y . A role for Rab5 activity in the biogenesis of endosomal and lysosomal compartments. . Biochem. Biophys. Res. Commun. . 364 . 1 . 40–7 . 2007 . 17927960 . 10.1016/j.bbrc.2007.09.089 .

Notes and References

1. Wilson DB, Wilson MP . Identification and subcellular localization of human rab5b, a new member of the ras-related superfamily of GTPases . J Clin Invest . 89 . 3 . 996–1005 . Apr 1992 . 1541686 . 442949 . 10.1172/JCI115683 .
2. Chiariello M, Bruni CB, Bucci C . The small GTPases Rab5a, Rab5b and Rab5c are differentially phosphorylated in vitro . FEBS Lett . 453 . 1–2 . 20–4 . Aug 1999 . 10403367 . 10.1016/S0014-5793(99)00686-9 . 30308802 .
3. Web site: Entrez Gene: RAB5B RAB5B, member RAS oncogene family.