RAB3B explained

Ras-related protein Rab-3B is a protein that in humans is encoded by the RAB3B gene.^[1]

Interactions

RAB3B has been shown to interact with RPH3A.^{[2] [3]}

Further reading

• Rousseau-Merck MF, Zahraoui A, Touchot N, Tavitian A, Berger R . Chromosome assignment of four RAS-related RAB genes . Human Genetics . 86 . 4 . 350–4 . February 1991 . 1999336 . 10.1007/BF00201831 . 30730416 .
• Zahraoui A, Touchot N, Chardin P, Tavitian A . The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion . The Journal of Biological Chemistry . 264 . 21 . 12394–401 . July 1989 . 10.1016/S0021-9258(18)63872-4 . 2501306 . free .
• Weber E, Berta G, Tousson A, St John P, Green MW, Gopalokrishnan U, Jilling T, Sorscher EJ, Elton TS, Abrahamson DR . Expression and polarized targeting of a rab3 isoform in epithelial cells . The Journal of Cell Biology . 125 . 3 . 583–94 . May 1994 . 8175882 . 2119989 . 10.1083/jcb.125.3.583 .
• Weber E, Jilling T, Kirk KL . Distinct functional properties of Rab3A and Rab3B in PC12 neuroendocrine cells . The Journal of Biological Chemistry . 271 . 12 . 6963–71 . March 1996 . 8636125 . 10.1074/jbc.271.12.6963 . free .
• Regazzi R, Ravazzola M, Iezzi M, Lang J, Zahraoui A, Andereggen E, Morel P, Takai Y, Wollheim CB . Expression, localization and functional role of small GTPases of the Rab3 family in insulin-secreting cells . Journal of Cell Science . 109 (Pt 9) . 9 . 2265–73 . September 1996 . 10.1242/jcs.109.9.2265 . 8886977 .
• Sidhu RS, Bhullar RP . Rab3B in human platelet is membrane bound and interacts with Ca(2+)/calmodulin . Biochemical and Biophysical Research Communications . 289 . 5 . 1039–43 . December 2001 . 11741295 . 10.1006/bbrc.2001.6113 .
• van IJzendoorn SC, Tuvim MJ, Weimbs T, Dickey BF, Mostov KE. Keith E. Mostov . Direct interaction between Rab3b and the polymeric immunoglobulin receptor controls ligand-stimulated transcytosis in epithelial cells . Developmental Cell . 2 . 2 . 219–28 . February 2002 . 11832247 . 10.1016/S1534-5807(02)00115-6 . free .
• Fukuda M . Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2 . The Journal of Biological Chemistry . 278 . 17 . 15373–80 . April 2003 . 12578829 . 10.1074/jbc.M212341200 . free .
• Yamamoto Y, Nishimura N, Morimoto S, Kitamura H, Manabe S, Kanayama HO, Kagawa S, Sasaki T . Distinct roles of Rab3B and Rab13 in the polarized transport of apical, basolateral, and tight junctional membrane proteins to the plasma membrane . Biochemical and Biophysical Research Communications . 308 . 2 . 270–5 . August 2003 . 12901864 . 10.1016/S0006-291X(03)01358-5 .
• Matsumoto M, Miki T, Shibasaki T, Kawaguchi M, Shinozaki H, Nio J, Saraya A, Koseki H, Miyazaki M, Iwanaga T, Seino S . Noc2 is essential in normal regulation of exocytosis in endocrine and exocrine cells . Proceedings of the National Academy of Sciences of the United States of America . 101 . 22 . 8313–8 . June 2004 . 15159548 . 420391 . 10.1073/pnas.0306709101 . 2004PNAS..101.8313M . free .
• Barrios-Rodiles M, Brown KR, Ozdamar B, Bose R, Liu Z, Donovan RS, Shinjo F, Liu Y, Dembowy J, Taylor IW, Luga V, Przulj N, Robinson M, Suzuki H, Hayashizaki Y, Jurisica I, Wrana JL . High-throughput mapping of a dynamic signaling network in mammalian cells . Science . 307 . 5715 . 1621–5 . March 2005 . 15761153 . 10.1126/science.1105776 . 2005Sci...307.1621B . 39457788 .
• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M . Towards a proteome-scale map of the human protein-protein interaction network . Nature . 437 . 7062 . 1173–8 . October 2005 . 16189514 . 10.1038/nature04209 . 2005Natur.437.1173R . 4427026 .

Notes and References

1. Web site: Entrez Gene: RAB3B RAB3B, member RAS oncogene family.
2. Fukuda M . Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2 . The Journal of Biological Chemistry . 278 . 17 . 15373–80 . April 2003 . 12578829 . 10.1074/jbc.M212341200 . free .
3. Weber E, Jilling T, Kirk KL . Distinct functional properties of Rab3A and Rab3B in PC12 neuroendocrine cells . The Journal of Biological Chemistry . 271 . 12 . 6963–71 . March 1996 . 8636125 . 10.1074/jbc.271.12.6963 . free .