RAB38 explained

Ras-related protein Rab-38 is a protein that in humans is encoded by the RAB38 gene.^{[1] [2]}

In melanocytic cells RAB38 gene expression may be regulated by MITF.^[3]

Further reading

• Chi A . Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes . J. Proteome Res. . 5 . 11 . 3135–44 . 2007 . 17081065 . 10.1021/pr060363j . vanc. Valencia JC . Hu ZZ . 3 . Watabe . Hidenori . Yamaguchi . Hiroshi . Mangini . Nancy J. . Huang . Hongzhan . Canfield . Victor A. . Cheng . Keith C. .
• Barrios-Rodiles M . High-throughput mapping of a dynamic signaling network in mammalian cells . Science . 307 . 5715 . 1621–5 . 2005 . 15761153 . 10.1126/science.1105776 . vanc. Brown KR . Ozdamar B . 3 . Bose . R . Liu . Z . Donovan . RS . Shinjo . F . Liu . Y . Dembowy . J . 2005Sci...307.1621B . 39457788 .
• Gerhard DS . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . vanc. Wagner L . Feingold EA . 3 . Shenmen . CM . Grouse . LH . Schuler . G . Klein . SL . Old . S . Rasooly . R .
• Suzuki T, Miyamura Y, Inagaki K, Tomita Y . Characterization of the human RAB38 and RAB7 genes: exclusion of new major pathological loci for Japanese OCA . J. Dermatol. Sci. . 32 . 2 . 131–6 . 2004 . 12850305 . 10.1016/S0923-1811(03)00071-9 .
• Basrur V . Proteomic analysis of early melanosomes: identification of novel melanosomal proteins . J. Proteome Res. . 2 . 1 . 69–79 . 2003 . 12643545 . 10.1021/pr025562r . vanc. Yang F . Kushimoto T . 3 . Higashimoto . Youichiro . Yasumoto . Ken-Ichi . Valencia . Julio . Muller . Jacqueline . Vieira . Wilfred D. . Watabe . Hidenori .
• Strausberg RL . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . vanc. Feingold EA . Grouse LH . 3 . Derge . JG . Klausner . RD . Collins . FS . Wagner . L . Shenmen . CM . Schuler . GD . 2002PNAS...9916899M . free .
• Osanai K . Expression and Localization of a Novel Rab Small G Protein (Rab38) in the Rat Lung . Am. J. Pathol. . 158 . 5 . 1665–75 . 2001 . 11337364 . 10.1016/S0002-9440(10)64122-3. 1891947 . vanc. Iguchi M . Takahashi K . 3 . Nambu . Y . Sakuma . T . Toga . H . Ohya . N . Shimizu . H . Fisher . JH .

Notes and References

1. Jager D, Stockert E, Jager E, Gure AO, Scanlan MJ, Knuth A, Old LJ, Chen YT . Serological cloning of a melanocyte rab guanosine 5'-triphosphate-binding protein and a chromosome condensation protein from a melanoma complementary DNA library . Cancer Res . 60 . 13 . 3584–91 . Aug 2000 . 10910072 .
2. Web site: Entrez Gene: RAB38 RAB38, member RAS oncogene family.
3. Hoek KS . Novel MITF targets identified using a two-step DNA microarray strategy . Pigment Cell Melanoma Res. . 21 . 6 . 665–76 . 2008 . 19067971 . 10.1111/j.1755-148X.2008.00505.x . vanc. Schlegel NC . Eichhoff OM . 3 . Widmer . Daniel S. . Praetorius . Christian . Einarsson . Steingrimur O. . Valgeirsdottir . Sigridur . Bergsteinsdottir . Kristin . Schepsky . Alexander . 24698373 . free .