The R506 is a Regional Route in South Africa.[1]
| Country: | ZAF |
| Type: | R |
| Route: | 506 |
| Length Km: | 146 |
| Direction A: | North-east |
| Terminus A: | near Delareyville |
| Junction: | in Schweizer-Reneke |
| Direction B: | South-west |
| Terminus B: | near Christiana |
| Previous Type: | R |
| Previous Route: | 505 |
| Next Type: | R |
| Next Route: | 507 |
It runs north-east south-west. The northern end takes origin from the R507 just south-east of Delareyville, North West. The first town it passes through is Migdol. From there it reaches Schweizer-Reneke. It becomes co-signed with the R34 and while so designated crosses the R504 and the Harts River. South of the town, the R506 splits and exits the town south-south-west and continues to Christiana, where it ends at a t-junction with the R708.