| Country: | ZAF |
| Type: | R |
| Route: | 390 |
| Length Round: | 0 |
| Direction A: | North |
| Terminus A: | Bethulie |
| Direction B: | South |
| Terminus B: | Cradock |
| Towns: | Oviston, Venterstad, Steynsburg, Hofmeyr, through Fish River Valley |
| Previous Type: | R |
| Previous Route: | 389 |
| Next Type: | R |
| Next Route: | 391 |
The R390 is a Regional Route in South Africa that connects Cradock with Bethulie. It is co-signed with the R56 to Steynsburg for 10 kilometres.[1]
Part of the route from Oviston (Gariep Dam) to Cradock forms part of the shortest road route from Johannesburg to Gqeberha.