R1162-like plasmid antisense RNA explained
| R1162-like plasmid antisense RNA |
| Symbol: | Plasmid_R1162 |
| Rfam: | RF00043 |
| Rna Type: | Gene
- antisense
|
| Tax Domain: | Bacteria |
R1162-like plasmid antisense RNA is a 75-base RNA molecule which negatively regulates the RepI region of the plasmid.[1] The protein product of this gene region, along with another protein, controls the copy number of the 8.75kB R1162 plasmid.[2]
Experimental evidence has shown that in Escherichia coli, when levels of this RNA are decreased, the plasmid copy number of R1162 is increased.
Notes and References
- Kim K, Meyer RJ . Copy-number of broad host-range plasmid R1162 is regulated by a small RNA . Nucleic Acids Research . 14 . 20 . 8027–8046 . October 1986 . 2430262 . 311832 . 10.1093/nar/14.20.8027 .
- Kim K, Meyer RJ . Copy number of the broad host-range plasmid R1162 is determined by the amounts of essential plasmid-encoded proteins . Journal of Molecular Biology . 185 . 4 . 755–767 . October 1985 . 2932556 . 10.1016/0022-2836(85)90060-9 .
