| Río Mayo | |
| Native Name Lang: | es |
| Settlement Type: | Town |
| Pushpin Map: | Argentina Chubut Province |
| Pushpin Map Caption: | Location of Río Mayo in Argentina |
| Coordinates: | -45.6869°N -70.26°W |
| Subdivision Type: | Country |
| Subdivision Name: |  Argentina |
| Subdivision Type1: | Province |
| Subdivision Name1: | Chubut |
| Subdivision Type2: | Department |
| Subdivision Name2: | Río Senguer |
| Leader Title: | Mayor |
| Unit Pref: | Metric |
| Elevation M: | 460 |
| Population Footnotes: | [1] |
| Population Total: | 2791 |
| Population As Of: | 2010 |
| Population Density Km2: | auto |
| Timezone1: | ART |
| Utc Offset1: | -3 |
| Postal Code Type: | CPA base |
| Postal Code: | U9030 |
| Area Code Type: | Dialing code |
| Area Code: | +54 2903 |
| Blank Name Sec1: | Climate |
| Blank Info Sec1: | Csc/Dsc |
Río Mayo is a town located in the Río Senguer Department, in southwest Chubut Province, Argentina. It is an obligatory stopover of the Central Corridor towards Chile, close to two border crossings, one through the town of Lago Blanco to Balmaceda, Chile, and the other through Aldea Beleiro.
Río Mayo has the essential services for the visitor and also allows the practice of activities such as sport fishing, horseback riding, mountain biking and hiking.
The Chubut town of Río Mayo has a harsh and rigorous climate for most of the year (the first frosts occur in March and April), characterized by prolonged cold and extremely hostile winters with an absolute minimum temperature of -27º C and freezing maximum temperatures, negative down to -21º C.[2]